CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001826
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Para-aminobenzoate synthase glutamine amidotransferase component II 
Protein Synonyms/Alias
 ADC synthase 
Gene Name
 pabA 
Gene Synonyms/Alias
 b3360; JW3323 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
43LADIDALKPQKIVISacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine. 
Sequence Annotation
 DOMAIN 1 187 Glutamine amidotransferase type-1.
 ACT_SITE 79 79
 ACT_SITE 168 168
 ACT_SITE 170 170  
Keyword
 Complete proteome; Folate biosynthesis; Glutamine amidotransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 187 AA 
Protein Sequence
MILLIDNYDS FTWNLYQYFC ELGADVLVKR NDALTLADID ALKPQKIVIS PGPCTPDEAG 60
ISLDVIRHYA GRLPILGVCL GHQAMAQAFG GKVVRAAKVM HGKTSPITHN GEGVFRGLAN 120
PLTVTRYHSL VVEPDSLPAC FDVTAWSETR EIMGIRHRQW DLEGVQFHPE SILSEQGHQL 180
LANFLHR 187 
Gene Ontology
 GO:0046820; F:4-amino-4-deoxychorismate synthase activity; IEA:EC.
 GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.
 GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
 GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR017926; GATASE.
 IPR006221; TrpG/PapA_dom. 
Pfam
 PF00117; GATase 
SMART
  
PROSITE
 PS51273; GATASE_TYPE_1 
PRINTS