UniProt Accession

 H3BN55_HUMAN; H3BN55 

Genbank Protein ID

 AC011912; AC018926 

Genbank Nucleotide ID

  

Protein Name

 Ras-related protein Rab-27A 

Protein Synonyms/Alias

  

Gene Name

 RAB27A 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
33	LYQYTDGKFNSKFIT	ubiquitination	[1]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 185 AA 

Protein Sequence

Gene Ontology

 GO:0016324; C:apical plasma membrane; IEA:Compara.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0042470; C:melanosome; IEA:Compara.
 GO:0001750; C:photoreceptor outer segment; IEA:Compara.
 GO:0030667; C:secretory granule membrane; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:Compara.
 GO:0007596; P:blood coagulation; IEA:Compara.
 GO:0043316; P:cytotoxic T cell degranulation; IEA:Compara.
 GO:0030318; P:melanocyte differentiation; IEA:Compara.
 GO:0032402; P:melanosome transport; IEA:Compara.
 GO:0043320; P:natural killer cell degranulation; IEA:Compara.
 GO:0006605; P:protein targeting; IEA:Compara.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 

Pfam

 PF00071; Ras 

SMART

 SM00175; RAB 

PROSITE

  

PRINTS

 PR00449; RASTRNSFRMNG.