CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010075
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 DNA-directed RNA polymerase subunit beta' 
Protein Synonyms/Alias
 RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' 
Gene Name
 rpoC 
Gene Synonyms/Alias
 MPN_515; MP327 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
72DYECACGKFKKIKYRacetylation[1]
161DPKIMPFKFKEVLDLacetylation[1]
256DLNYEFSKLNDALRKacetylation[1]
265NDALRKAKKDSVEDAacetylation[1]
273KDSVEDAKVKKILRQacetylation[1]
439LMILKLFKPFIIHGLacetylation[1]
1060IFEVVAPKDYERCVIacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome; Transcription; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1290 AA 
Protein Sequence
MTKRNKKNNK LYKNIKAIKL SIASNDTILN WSEGEVTKAE TINYKSLKPE PGGLFDEAIF 60
GPVKDYECAC GKFKKIKYRG VRCDRCGVWV TESIVRRERM GHIALVSPVA HIWMSKELPS 120
PSKISLVLNI SYKEVEQVLY FVNYIVLDTG KIKDPKIMPF KFKEVLDLAG KGSLTTRQKM 180
RRVIGYIFRN LIKNRSSEDY RKGKIFYESL KNSSLPFSLN DAFNYIKKYT GFRVGIGAEA 240
ILELLNKIDL NYEFSKLNDA LRKAKKDSVE DAKVKKILRQ LETISWFRNS KLHPKNMILH 300
TVPVIPPDIR PIIQLDGAKF TTSDINNFYR RVIIRNDRLR RILEDGTVPA IVVNNEKRLL 360
QESVDALFDN SSRHKPALSK DKRSLKSLTD RLKGKQGLFR HNLLGKRVDY SGRSVIVVGP 420
ELKMYEVGIP ALMILKLFKP FIIHGLINKF DSNGNEIRPI ASSIRQAEDM IKNQDDLIWG 480
IVYDVIKDRP VLLNRAPTLH RLGIQAFEPR IVDGKAIRLH PLVTTAFNAD FDGDQMAVHV 540
PLSENAVNEA RAILLASKHI LGLKDGRPIV TPTQDMVLGN YYLTTERKGQ TGEGIIFGTV 600
HEARAAYEAG KVHLHAIVGI STKAFPNKHF EAQGTLITTV GKIIFNDVLG DNIPYINEGE 660
FDEHACPQKF IVPPSGDVRA AIAAHQVLPA FGKKVISKLI DLLYTVVEFK DLPRILENIK 720
ALGFKYSTHS STTVSVFDIP KYSNKQQYFD EADQQVLKYK QFYNKGLLTD DERYKRVVKL 780
WNGVKEKVSS EIQDLIKREE YRDNSIVVMA DSGARGNISN FTQLFGMRGL MSKSFNYERN 840
NQSKIIKDTI EVPIKHSFLE GLTINEYFNS SYGARKGMTD TAMKTAKSGY MTRKLVDATH 900
ELIINHDDCG TRKGIVVEAI VETKTRSLVE SLFDRIVNRY TIGPILDPET KAEIVPANSL 960
ITQELAKQIC ATSIKQVLVR SVIYCERENG VCQYCFGVDL STGKLVELGT AVGVIAAQSI 1020
GEPGTQLTMR TFHTGGVSTE NNLAQGFERL KQIFEVVAPK DYERCVISEV KGVVKSITTT 1080
QNAQEVLIES SVDERTYSIP FSAQLRVKVG DAVELGSKIT EGSIDIRQLL RVAGIQRVRQ 1140
YMIVEIQKVY RIQGIEIADK YVEIIIRQLT SLLQVTDAGS SNLFVGQLVH SHHLNELNKS 1200
LLLSGKMPVI AINQVFGIDE AASKSNSFLS AASFQDTKKI LTDAAVKTQV DYLLGLKENV 1260
IIGGKIPAGT GFLTDEELAY LGAKTVQEEY 1290 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:HAMAP.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:HAMAP.
 GO:0006351; P:transcription, DNA-dependent; IEA:HAMAP. 
Interpro
 IPR009010; Asp_de-COase-like_dom.
 IPR012754; DNA-dir_RpoC_beta_prime.
 IPR000722; RNA_pol_asu.
 IPR006592; RNA_pol_N.
 IPR007080; RNA_pol_Rpb1_1.
 IPR007066; RNA_pol_Rpb1_3.
 IPR007083; RNA_pol_Rpb1_4.
 IPR007081; RNA_pol_Rpb1_5. 
Pfam
 PF04997; RNA_pol_Rpb1_1
 PF00623; RNA_pol_Rpb1_2
 PF04983; RNA_pol_Rpb1_3
 PF05000; RNA_pol_Rpb1_4
 PF04998; RNA_pol_Rpb1_5 
SMART
 SM00663; RPOLA_N 
PROSITE
  
PRINTS