| Tag | Content |
|---|
| CPLM ID | CPLM-019316 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 419 |
Protein Synonyms/Alias | |
Gene Name | ZNF419 |
Gene Synonyms/Alias | ZNF419A |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 166 | LQSREVGKALLISSG | ubiquitination | [1] | | 215 | CGKAFGQKYLLVQHQ | ubiquitination | [1] | | 332 | SFNSSLMKHQRIHTG | ubiquitination | [1] |
|
Reference | [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C. Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [ PMID: 21890473] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 27 98 KRAB.
ZN_FING 203 225 C2H2-type 1.
ZN_FING 231 253 C2H2-type 2.
ZN_FING 259 281 C2H2-type 3.
ZN_FING 287 309 C2H2-type 4.
ZN_FING 315 337 C2H2-type 5.
ZN_FING 343 365 C2H2-type 6.
ZN_FING 371 393 C2H2-type 7.
ZN_FING 399 421 C2H2-type 8.
ZN_FING 427 449 C2H2-type 9.
ZN_FING 455 477 C2H2-type 10.
ZN_FING 483 505 C2H2-type 11. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 510 AA |
Protein Sequence | MAAAALRDPA QVPVAADLLT DHEEGYVTFE DVAVYFSQEE WRLLDDAQRL LYRNVMLENF 60
TLLASLGLAS SKTHEITQLE SWEEPFMPAW EVVTSAIPRG CWHGAEAEEA PEQIASVGLL 120
SSNIQQHQKQ HCGEKPLKRQ EGRVPVLRSC KVHLSEKSLQ SREVGKALLI SSGVLKHQVT 180
HTGEKSHRSS KSREAFHAGK RHYKCSECGK AFGQKYLLVQ HQRLHAGKKT YECSECGKLF 240
RDMSNLFIHQ IVHTGERPYG CSNCGKSFSR NAHLIEHQRV HTGEKPFTCS ECGKAFRHNS 300
TLVQHHKIHT GVRPYECSEC GKLFSFNSSL MKHQRIHTGE RPYKCSECGK FYSHKSNLIK 360
HWRVHTGERP YKCSDCGKFF TQCSSLMQHQ KVHTGEKPFK CNECGRFFRE NSTLVRHQRV 420
HTGAKPYECR ECGKFFSQSS TLMQHRKVHI GEKPFKCNEC GRLFRENSSL VKHQRVHTGA 480
KPYECRECGK FFRHNSSLFK HRRIHTGEMQ 510 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |