CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007039
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pre-rRNA-processing protein RIX1 
Protein Synonyms/Alias
 Involved in processing IST2 protein 2; Ribosomal export protein 1 
Gene Name
 RIX1 
Gene Synonyms/Alias
 IPI2; YHR197W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
676EPKHEVPKVVDDTAIacetylation[1]
685VDDTAIFKKRSVEEVacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA. 
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 763 AA 
Protein Sequence
MSEEFIAVST LARNLEIAKG NEFHTILATL RSPVYINEQL LKSELSFLVT KILKLIRSGN 60
DFDLWKGCHT SVVTCAYNPL VLSTHGGQLL AAIYSRLEQK TGFYSSVISS SHGKQLFNTL 120
ISSVAIIIDL MKNKPTLSRE ALVPKLKAII PTLITLSQYE PELVLPVLQR ILKRNTTTFK 180
PFTNKFRTVL INLIISDYAS LGTKTQRLVC ENFAYLHLLK IQVSDTSDDE TQAHHKIYAD 240
SNWRTGLMSI LSQFKPIIQL CGEILDFEQD NELYKLIKSL PVIDESNNKE EFLPSLKLDF 300
NAPLTLWEIP QRLSLLADML VAFISLPTPF PIRVPLGGIN SLCEVLLGVS NKYLPLKKEL 360
RHDNELNGVI NTILPQIQFQ GIRLWEIMVS KYGKCGLSFF EGILSSIELF IPLKKKSNNE 420
IDFNVVGSLK FEFATVFRLV NMILSHLGHQ LNIISVISQL IEVALFLSHD KTLIDSLFKN 480
RKSIMKQQTK TKQSKRSKSA EGAFSDIYTH PELFVCKNSM NWFNEINDFF ITALNNWILP 540
STPHIQILKY SITQSLRLKE RFGYIPESFV NLLRCEVLHP GSERVSILPI AISLLKNIND 600
DMFELLCHPK VPVGMVYQLH KPLDLGEDGE VRDDINKKEV ETNESSSNAN TGLETLKALE 660
NLENVTIPEP KHEVPKVVDD TAIFKKRSVE EVIERESTSS HKKVKFVEET TVDNGEELIV 720
KKAVSQTKEE EKPMEDSEDE EQEEFEIPAI ELSDDEEEEE EEE 763 
Gene Ontology
 GO:0005829; C:cytosol; IDA:SGD.
 GO:0005654; C:nucleoplasm; IDA:SGD.
 GO:0097344; C:Rix1 complex; IDA:SGD.
 GO:0003682; F:chromatin binding; IDA:SGD.
 GO:0006267; P:pre-replicative complex assembly; IMP:SGD.
 GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.
 GO:0000027; P:ribosomal large subunit assembly; IMP:SGD.
 GO:0000054; P:ribosomal subunit export from nucleus; IMP:SGD.
 GO:0006364; P:rRNA processing; IMP:SGD. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS