UniProt Accession

 O92597_HHV8; O92597 

Genbank Protein ID

 AF072866; AF091348; AJ011499 

Genbank Nucleotide ID

 AAD21530.1; AAD25316.1; CAA09627.1 

Protein Name

 K8 alpha 

Protein Synonyms/Alias

 K8 protein; Putative bZIP transcription factor 

Gene Name

 k8 

Gene Synonyms/Alias

 KIE-1 

Created Date

 July 27, 2013 

Organism

 Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus) 

NCBI Taxa ID

 37296 

Lysine Modification

Position	Peptide	Type	References
145	ERLCTKAKQGAGRPV	acetylation	[1]
158	PVPASVVKAEVCDQS	sumoylation	[1, 2, 3]

Reference

 [1] Repression of interferon-α stimulated genes expression by Kaposi's sarcoma-associated herpesvirus K-bZIP protein.
 Lefort S, Gravel A, Flamand L.
 Virology. 2010 Dec 5;408(1):14-30. [PMID: 20870261]
 [2] Kaposi's sarcoma-associated herpesvirus K-bZIP represses gene transcription via SUMO modification.
 Izumiya Y, Ellison TJ, Yeh ET, Jung JU, Luciw PA, Kung HJ.
 J Virol. 2005 Aug;79(15):9912-25. [PMID: 16014952]
 [3] Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a SUMO E3 ligase that is SIM-dependent and SUMO-2/3-specific.
 Chang PC, Izumiya Y, Wu CY, Fitzgerald LD, Campbell M, Ellison TJ, Lam KS, Luciw PA, Kung HJ.
 J Biol Chem. 2010 Feb 19;285(8):5266-73. [PMID: 20034935] 

Functional Description

  

Sequence Annotation

  

Keyword

  

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 237 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR010805; KSHV_K8. 

Pfam

 PF07188; KSHV_K8 

SMART

  

PROSITE

  

PRINTS