CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037113
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 UTP--glucose-1-phosphate uridylyltransferase 
Protein Synonyms/Alias
  
Gene Name
 UGP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
102IQPYEKIKARGLPDNubiquitination[1]
300NKTRADVKGGTLTQYubiquitination[1, 2]
310TLTQYEGKLRLVEIAubiquitination[1]
321VEIAQVPKAHVDEFKubiquitination[1]
328KAHVDEFKSVSKFKIacetylation[3, 4]
328KAHVDEFKSVSKFKIubiquitination[1]
440FPTVPLVKLGSSFTKubiquitination[1]
447KLGSSFTKVQDYLRRacetylation[3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [4] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 517 AA 
Protein Sequence
MLLYPAGFSF ASLKSDLSKA MSQDGASQFQ EVIRQELELS VKKELEKILT TASSHEFEHT 60
KKDLDGFRKL FHRFLQEKGP SVDWGKIQRP PEDSIQPYEK IKARGLPDNI SSVLNKLVVV 120
KLNGGLGTSM GCKGPKSLIG VRNENTFLDL TVQQIEHLNK TYNTDVPLVL MNSFNTDEDT 180
KKILQKYNHC RVKIYTFNQS RYPRINKESL LPVAKDVSYS GENTEAWYPP GHGDIYASFY 240
NSGLLDTFIG EGKEYIFVSN IDNLGATVDL YILNHLMNPP NGKRCEFVME VTNKTRADVK 300
GGTLTQYEGK LRLVEIAQVP KAHVDEFKSV SKFKIFNTNN LWISLAAVKR LQEQNAIDME 360
IIVNAKTLDG GLNVIQLETA VGAAIKSFEN SLGINVPRSR FLPVKTTSDL LLVMSNLYSL 420
NAGSLTMSEK REFPTVPLVK LGSSFTKVQD YLRRFESIPD MLELDHLTVS GDVTFGKNVS 480
LKGTVIIIAN HGDRIDIPPG AVLENKIVSG NLRILDH 517 
Gene Ontology
 GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro. 
Interpro
 IPR002618; UDPGP_trans.
 IPR016267; UDPGP_trans_subgr. 
Pfam
 PF01704; UDPGP 
SMART
  
PROSITE
  
PRINTS