CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026208
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Growth factor receptor-bound protein 10 
Protein Synonyms/Alias
  
Gene Name
 Grb10 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
370NYRIPQRKGLPPPFNubiquitination[1]
464EESHRIIKQQGLVDGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 550 AA 
Protein Sequence
MNNDINSSVE SLNSACNMQS DTDTAPLLED GQHASNQGAA SSSRGQPQAS PRQKMQRSQP 60
VHILRRLQEE DQQLRTASLP AIPNPFPELT GAAPGSPPSV APSSLPPPPS QPPAKHFPPG 120
FQLSKLTRPG LWTKTTARFS KKQPKNQCPT DTVNPVARMP TSQMEKLRLR KDVKVFSEDG 180
TSKVVEILTD MTARDLCQLL VYKSHCVDDN SWTLVEHHPQ LGLERCLEDH EIVVQVESTM 240
PSESKFLFRK NYAKYEFFKN PVNFFPDQMV NWCQQSNGGQ AQLLQEPRHL QLLADLEESS 300
IFYLIAGKKQ YNAPNEHGMC IKPNKAKTEM KELRLLCAED EQIRTCWMTA FRLLKYGMLL 360
YQNYRIPQRK GLPPPFNAPM RSVSENSLVA MDFSGQIGRV IDNPAEAQSA ALEEGHAWRK 420
RSTRMNILSS QSPLHPSTLN AVIHRTQHWF HGRISREESH RIIKQQGLVD GLFLLRDSQS 480
NPKAFVLTLC HHQKIKNFQI LPCEDDGQTF FTLDDGNTKF SDLIQLVDFY QLNKGVLPCK 540
LKHHCIRVAL 550 
Gene Ontology
 GO:0005829; C:cytosol; TAS:MGI.
 GO:0005070; F:SH3/SH2 adaptor activity; IDA:MGI.
 GO:0048009; P:insulin-like growth factor receptor signaling pathway; IPI:MGI. 
Interpro
 IPR015042; BPS-dom.
 IPR000159; Ras-assoc.
 IPR000980; SH2. 
Pfam
 PF08947; BPS
 PF00788; RA
 PF00017; SH2 
SMART
 SM00314; RA
 SM00252; SH2 
PROSITE
 PS50200; RA
 PS50001; SH2 
PRINTS
 PR00401; SH2DOMAIN.