| Tag | Content |
|---|
| CPLM ID | CPLM-015257 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | E3 ubiquitin-protein ligase TRIM37 |
Protein Synonyms/Alias | Tripartite motif-containing protein 37 |
Gene Name | Trim37 |
Gene Synonyms/Alias | Kiaa0898 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 411 | RSPTFFQKCRDQHWY | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | E3 ubiquitin-protein ligase (By similarity). |
Sequence Annotation | DOMAIN 276 403 MATH.
ZN_FING 15 55 RING-type; degenerate.
ZN_FING 90 132 B box-type. |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Ligase; Metal-binding; Peroxisome; Reference proteome; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 961 AA |
Protein Sequence | MDEQSVESIA EVFRCFICME KLRDARLCPH CSKLCCFSCI RRWLTEQRAQ CPHCRAPLQL 60
RELVNCRWAE EVTQQLDTLQ LCSLTKHEEN EKDKCENHHE KLSVFCWTCK KCICHQCALW 120
GGMHGGHTFK PLAEIYEQHV TKVNEEVAKL RRRLMELISL VQEVERNVEA VRNAKDERVR 180
EIRNAVEMMI ARLDTQLKNK LITLMGQKTS LTQETELLES LLQEVEHQLR SCSKSELISK 240
SSEILMMFQQ VHRKPMASFV TTPVPPDFTS ELVPSYDSAT FVLENFSTLR QRADPVYSPP 300
LQVSGLCWRL KVYPDGNGVV RGYYLSVFLE LSAGLPETSK YEYRVEMVHQ SCNDPTKNII 360
REFASDFEVG ECWGYNRFFR LDLLANEGYL NRQNDTVILR FQVRSPTFFQ KCRDQHWYIT 420
QLEAAQTGYI QQINNLKERL TIELSRTQKS RDLSPPDNHL SPQNDDSPET RTKKAGSCSD 480
MLLEGGPTCA SVRETKEDED EEEKIQNEDY HHELSDGDLD LDLVGEDEVN HLDGSSSSAS 540
STATSNTEEN DIDEETMSGE NDVEYNSMEL EEGELMEDAA AAGPPGSSHS YVGASSRMSR 600
RTHLCSAATS SLLDIDPLIL IHLLDLKDRS SMENLWGLQP RPSASLLQPT ASYSRKDKDQ 660
RKQQAMWRVP SDLKMLKRLK TQMAEVRCMK TDVKTTLSDI KGSSVASTDM QTNLFCADQA 720
ALTTCGPENS GRLQDLGMEL LAKSSVAGCY IRNPTNKKNS PKSARAIAGS LSLRRAVDSG 780
ENSRSKGDCQ VLAEGSSGSS QSGSRHSSPR ALTHGIIGDL LPKSEDRQCK ALDSDAVVVA 840
VFNGLPTVEK RRKMVTLGTN AKGGRLEGMQ MADLESHSEA GEVQPTLPEG ASAAPEEGMS 900
SDSDIECDTE NEEQEEHTSM GAFNDPFLAQ PPDEDSHSSF PDGEQIDPEN LHFNPDEGGG 960
R 961 |
Gene Ontology | GO:0016235; C:aggresome; IEA:Compara. GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0070842; P:aggresome assembly; IEA:Compara. GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Compara. GO:0051865; P:protein autoubiquitination; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |