| Tag | Content |
|---|
| CPLM ID | CPLM-037700 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | T-lymphoma invasion and metastasis-inducing protein 2 |
Protein Synonyms/Alias | |
Gene Name | TIAM2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 590 | KPVQRVLKYPLLLKE | ubiquitination | [1] | | 784 | ESKTNIVKVIRSILR | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1045 AA |
Protein Sequence | MDLFRMRCYL ASLQGGELPN PKSLLAAASR PSKLALGRLG ILSVSSFHAL VCSRDDSALR 60
KRTLSLTQRG RNKKGIFSSL KGLDTLARKG KEKRPSITQI FDSSGSHGFS GTQLPQNSSN 120
SSEVDELLHI YGSTVDGVPR DNAWEIQTYV HFQDNHGVTV GIKPEHRVED ILTLACKMRQ 180
LEPSHYGLQL RKLVDDNVEY CIPAPYEYMQ QQVYDEIEVF PLNVYDVQLT KTGSVCDFGF 240
AVTAQVDERQ HLSRIFISDV LPDGLAYGEG LRKGNEIMTL NGEAVSDLDL KQMEALFSEK 300
SVGLTLIARP PDTKATLCTS WSDSDLFSRD QKSLLPPPNQ SQLLEEFLDN FKKNTANDFS 360
NVPDITTGLK RSQTDGTLDQ VSHREKMEQT FRSAEQITAL CRSFNDSQAN GMEGPRENQD 420
PPPRSLARHL SDADRLRKVI QELVDTEKSY VKDLSCLFEL YLEPLQNETF LTQDEMESLF 480
GSLPEMLEFQ KVFLETLEDG ISASSDFNTL ETPSQFRKLL FSLGGSFLYY ADHFKLYSGF 540
CANHIKVQKV LERAKTDKAF KAFLDARNPT KQHSSTLESY LIKPVQRVLK YPLLLKELVS 600
LTDQESEEHY HLTEALKAME KVASHINEMQ KIYEDYGTVF DQLVAEQSGT EKEVTELSMG 660
ELLMHSTVSW LNPFLSLGKA RKDLELTVFV FKRAVILVYK ENCKLKKKLP SNSRPAHNST 720
DLDPFKFRWL IPISALQVRL GNPAGTENNS IWELIHTKSE IEGRPETIFQ LCCSDSESKT 780
NIVKVIRSIL RENFRRHIKC ELPLEKTCKD RLVPLKNRVP VSAKLAKCVF LTVASSRSLK 840
VLKNSSSNEW TGETGKGTLL DSDEGSLSSG TQSSGCPTAE GRQDSKSTSP GKYPHPGLAD 900
FADNLIKESD ILSDEDDDHR QTVKQGSPTK DIEIQFQRLR ISEDPDVHPE AEQQPGPESG 960
EGQKGGEQPK LVRGHFCPIK RKANSTKRDR GTLLKAQIRH QSLDSQSENA TIDLNSVLER 1020
EFSVQSLTSV VSEECFYETE SHGKS 1045 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0005543; F:phospholipid binding; IEA:InterPro. GO:0005057; F:receptor signaling protein activity; IEA:InterPro. GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. GO:0035556; P:intracellular signal transduction; IEA:InterPro. GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |