UniProt Accession

 USMG5_HUMAN; Q96IX5; B2R4N2; D3DR92 

Genbank Protein ID

 AY740522; AJ272056; AK311888; AL591408; CH471066; CH471066; CH471066; BC007087; BC072683; BC091507 

Genbank Nucleotide ID

 AAU89079.1; CAC81243.1; BAG34829.1; CAI16748.1; EAW49642.1; EAW49643.1; EAW49644.1; AAH07087.1; AAH72683.1; AAH91507.1 

Protein Name

 Up-regulated during skeletal muscle growth protein 5 

Protein Synonyms/Alias

 Diabetes-associated protein in insulin-sensitive tissues; HCV F-transactivated protein 2 

Gene Name

 USMG5 

Gene Synonyms/Alias

 DAPIT; HCVFTP2; PD04912 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
16	QYQFTGIKKYFNSYT	ubiquitination	[1, 2, 3]
17	YQFTGIKKYFNSYTL	ubiquitination	[1, 3, 4]
56	SKKTPAVKAT*****	ubiquitination	[5]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Plays a critical role in maintaining the ATP synthase population in mitochondria. 

Sequence Annotation

 MOD_RES 16 16 N6-acetyllysine (By similarity).
 MOD_RES 17 17 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; Membrane; Mitochondrion; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 58 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005753; C:mitochondrial proton-transporting ATP synthase complex; ISS:UniProtKB. 

Interpro

 IPR009125; DAPIT. 

Pfam

  

SMART

  

PROSITE

  

PRINTS

 PR01821; DAPIT.