UniProt Accession

 CSTFT_MOUSE; Q8C7E9; Q6A016; Q8BHH7; Q8C3W7; Q8R2Y1; Q9EPU3 

Genbank Protein ID

 AF322194; AK173002; AK034853; AK050407; AK082910; AK084696; BC026995 

Genbank Nucleotide ID

 AAG40327.1; BAD32280.1; BAC28855.1; BAC34240.1; BAC38683.1; BAC39256.1; AAH26995.1 

Protein Name

 Cleavage stimulation factor subunit 2 tau variant 

Protein Synonyms/Alias

 CF-1 64 kDa subunit tau variant; Cleavage stimulation factor 64 kDa subunit tau variant; CSTF 64 kDa subunit tau variant; TauCstF-64 

Gene Name

 Cstf2t 

Gene Synonyms/Alias

 Kiaa0689 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
189	MDPEIALKILHRKIH	ubiquitination	[1]
194	ALKILHRKIHVTPLI	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs. 

Sequence Annotation

 DOMAIN 16 94 RRM.
 REPEAT 428 432 1-1; approximate.
 REPEAT 433 437 1-2; approximate.
 REPEAT 438 442 1-3; approximate.
 REPEAT 443 446 1-4; approximate.
 REPEAT 447 451 1-5; approximate.
 REPEAT 452 456 1-6.
 REPEAT 457 461 1-7; approximate.
 REPEAT 462 466 1-8; approximate.
 REPEAT 508 512 2-1; approximate.
 REPEAT 513 517 2-2.
 REPEAT 518 522 2-3; approximate.
 REPEAT 523 527 2-4.
 REPEAT 528 532 2-5; approximate.
 REPEAT 533 537 2-6.
 REPEAT 538 542 2-7; approximate.
 REPEAT 543 547 2-8.
 REPEAT 548 551 2-9; approximate.
 REPEAT 552 556 2-10; approximate.
 REPEAT 557 560 2-11; approximate.
 REPEAT 561 565 2-12.
 REGION 428 466 8 X 5 AA tandem repeats of M-E-T-R-[AG].
 REGION 508 565 12 X 5 AA tandem repeats of G-[AT]-G-  

Keyword

 Complete proteome; mRNA processing; Nucleus; Reference proteome; Repeat; RNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 632 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IDA:MGI.
 GO:0006378; P:mRNA polyadenylation; TAS:MGI. 

Interpro

 IPR025742; CSTF2_hinge.
 IPR026896; CSTF_C.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 

Pfam

 PF14327; CSTF2_hinge
 PF14304; CSTF_C
 PF00076; RRM_1 

SMART

 SM00360; RRM 

PROSITE

 PS50102; RRM 

PRINTS