CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022309
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 SOHLH2 
Gene Synonyms/Alias
 TEB1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
85AEELEAIKLIRFGKKubiquitination[1]
128TEPLTMEKMSNVVKYubiquitination[1]
134EKMSNVVKYWTTCPSubiquitination[1]
145TCPSNTVKTENATGPubiquitination[1]
200LSEFEKNKKISLLHSubiquitination[1]
232RTLLPYVKGRKNDAAubiquitination[1]
250EATVDYVKYIREKISubiquitination[1]
277SNMRFCKKQQTPIELubiquitination[1]
370HTVRYYSKVTPSYDAubiquitination[1]
398SAMPPVSKLLPRHCTubiquitination[1]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
 Probable transcription factor, which may be involved in spermatogenesis and oogenesis (By similarity). 
Sequence Annotation
 DOMAIN 201 252 bHLH.  
Keyword
 Alternative splicing; Complete proteome; Developmental protein; Differentiation; DNA-binding; Nucleus; Oogenesis; Polymorphism; Reference proteome; Spermatogenesis; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 425 AA 
Protein Sequence
MASSIICQEH CQISGQAKID ILLVGDVTVG YLADTVQKLF ANIAEVTITI SDTKEAAALL 60
DDCIFNMVLL KVPSSLSAEE LEAIKLIRFG KKKNTHSLFV FIIPENFKGC ISGHGMDIAL 120
TEPLTMEKMS NVVKYWTTCP SNTVKTENAT GPEELGLPLQ RSYSEHLGYF PTDLFACSES 180
LRNGNGLELN ASLSEFEKNK KISLLHSSKE KLRRERIKYC CEQLRTLLPY VKGRKNDAAS 240
VLEATVDYVK YIREKISPAV MAQITEALQS NMRFCKKQQT PIELSLPGTV MAQRENSVMS 300
TYSPERGLQF LTNTCWNGCS TPDAESSLDE AVRVPSSSAS ENAIGDPYKT HISSAALSLN 360
SLHTVRYYSK VTPSYDATAV TNQNISIHLP SAMPPVSKLL PRHCTSGLGQ TCTTHPNCLQ 420
QFWAY 425 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR011598; bHLH_dom. 
Pfam
 PF00010; HLH 
SMART
 SM00353; HLH 
PROSITE
 PS50888; BHLH 
PRINTS