UniProt Accession

 C9J7E8_HUMAN; C9J7E8 

Genbank Protein ID

 AC008264; AC009362; AC009783; AC013434; AC018642 

Genbank Nucleotide ID

  

Protein Name

 Muskelin 

Protein Synonyms/Alias

  

Gene Name

 MKLN1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
156	YISQQEYKPRWSQII	ubiquitination	[1, 2]
168	QIIPKSTKGDGEDNR	ubiquitination	[1, 2, 3]
482	AAKDNPTKSLQEEEP	ubiquitination	[3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 643 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR006595; CTLH_C.
 IPR015915; Kelch-typ_b-propeller.
 IPR006594; LisH_dimerisation.
 IPR010565; Muskelin_N. 

Pfam

 PF06588; Muskelin_N 

SMART

 SM00667; LisH 

PROSITE

 PS50897; CTLH
 PS50896; LISH 

PRINTS