CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033310
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 DnaJ homolog subfamily A member 4 
Protein Synonyms/Alias
  
Gene Name
 DNAJA4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
32AYRKLALKYHPDKNPacetylation[1]
32AYRKLALKYHPDKNPubiquitination[2, 3]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Chaperone; Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 211 AA 
Protein Sequence
MVKETQYYDI LGVKPSASPE EIKKAYRKLA LKYHPDKNPD EGEKFKLISQ AYEVLSDPKK 60
RDVYDQGGEQ AIKEGGSGSP SFSSPMDIFD MFFGGGGRMA RERRGKNVVH QLSVTLEDLY 120
NGVTKKLALQ KNVICEKCEG VGGKKGSVEK CPLCKGRGMQ IHIQQIGPGM VQQIQTVCIE 180
CKGQGERINP KDRCESCSGA KVIREKKIIE V 211 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR001623; DnaJ_domain.
 IPR018253; DnaJ_domain_CS.
 IPR001305; HSP_DnaJ_Cys-rich_dom. 
Pfam
 PF00226; DnaJ
 PF00684; DnaJ_CXXCXGXG 
SMART
 SM00271; DnaJ 
PROSITE
 PS00636; DNAJ_1
 PS50076; DNAJ_2
 PS51188; ZF_CR 
PRINTS
 PR00625; JDOMAIN.