CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017541
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein boule-like 
Protein Synonyms/Alias
  
Gene Name
 BOLL 
Gene Synonyms/Alias
 BOULE 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
69YGSVKEVKIVNDRAGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity). 
Sequence Annotation
 DOMAIN 33 110 RRM.
 DOMAIN 164 194 DAZ-like.  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Developmental protein; Differentiation; Reference proteome; RNA-binding; Spermatogenesis; Translation regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 283 AA 
Protein Sequence
MQTSNQMQTD SLSPSPNPVS PVPLNNPTSA PRYGTVIPNR IFVGGIDFKT NESDLRKFFS 60
QYGSVKEVKI VNDRAGVSKG YGFVTFETQE DAQKILQEAE KLNYKDKKLN IGPAIRKQQV 120
GIPRSSIMPA AGTMYLTTST GYPYTYHNGV AYFHTPEVTS VPPPWPSRSV CSSPVMVAQP 180
IYQQPAYHYQ GIKQCHTRRW MDSLLPFTKC DEATTQYLPG QWQWSVPQPS ASSAPFLYLQ 240
PSEVIYQPVE IAQDGGCVPP PLSLMETSVP EPYSDHGVQA TYHQVYAPSA ITMPAPVMQP 300
EPIKCGAFII KTIGQLYSSS TDFLSNDPCV AEIQLQRTS 339 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0008494; F:translation activator activity; IDA:UniProtKB.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007126; P:meiosis; IDA:MGI.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0045948; P:positive regulation of translational initiation; IDA:UniProtKB.
 GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS