CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006132
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Low-affinity glucose transporter HXT1 
Protein Synonyms/Alias
  
Gene Name
 HXT1 
Gene Synonyms/Alias
 HOR4; YHR094C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
27ELESGRSKAMNTPEGubiquitination[1]
35AMNTPEGKNESFHDNubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Low-affinity glucose transporter. HXT1 is as well involved in the transport of mannose. 
Sequence Annotation
 MOD_RES 23 23 Phosphoserine.
 MOD_RES 38 38 Phosphoserine.
 MOD_RES 44 44 Phosphoserine.
 CARBOHYD 228 228 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Repeat; Sugar transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 570 AA 
Protein Sequence
MNSTPDLISP QKSNSSNSYE LESGRSKAMN TPEGKNESFH DNLSESQVQP AVAPPNTGKG 60
VYVTVSICCV MVAFGGFIFG WDTGTISGFV AQTDFLRRFG MKHHDGSHYL SKVRTGLIVS 120
IFNIGCAIGG IVLAKLGDMY GRRIGLIVVV VIYTIGIIIQ IASINKWYQY FIGRIISGLG 180
VGGITVLSPM LISEVAPSEM RGTLVSCYQV MITLGIFLGY CTNFGTKNYS NSVQWRVPLG 240
LCFAWALFMI GGMMFVPESP RYLVEAGRID EARASLAKVN KCPPDHPYIQ YELETIEASV 300
EEMRAAGTAS WGELFTGKPA MFQRTMMGIM IQSLQQLTGD NYFFYYGTIV FQAVGLSDSF 360
ETSIVFGVVN FFSTCCSLYT VDRFGRRNCL MWGAVGMVCC YVVYASVGVT RLWPNGQDQP 420
SSKGAGNCMI VFACFYIFCF ATTWAPIAYV VISECFPLRV KSKCMSIASA ANWIWGFLIS 480
FFTPFITGAI NFYYGYVFMG CMVFAYFYVF FFVPETKGLS LEEVNDMYAE GVLPWKSASW 540
VPVSKRGADY NADDLMHDDQ PFYKSLFSRK 570 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0005353; F:fructose transmembrane transporter activity; IMP:SGD.
 GO:0005354; F:galactose transmembrane transporter activity; TAS:SGD.
 GO:0005355; F:glucose transmembrane transporter activity; TAS:SGD.
 GO:0015578; F:mannose transmembrane transporter activity; TAS:SGD.
 GO:0015146; F:pentose transmembrane transporter activity; IMP:SGD. 
Interpro
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005828; Sub_transporter.
 IPR003663; Sugar/inositol_transpt.
 IPR005829; Sugar_transporter_CS. 
Pfam
 PF00083; Sugar_tr 
SMART
  
PROSITE
 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1
 PS00217; SUGAR_TRANSPORT_2 
PRINTS
 PR00171; SUGRTRNSPORT.