UniProt Accession

 RL11_RAT; P62914; P25121; P39026; Q9Y674 

Genbank Protein ID

 X62146 

Genbank Nucleotide ID

 CAA44072.1 

Protein Name

 60S ribosomal protein L11 

Protein Synonyms/Alias

  

Gene Name

 Rpl11 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
38	DRLTRAAKVLEQLTG	acetylation	[1]
52	GQTPVFSKARYTVRS	acetylation	[1]
78	HCTVRGAKAEEILEK	acetylation	[1]
85	KAEEILEKGLKVREY	acetylation	[1]
88	EILEKGLKVREYELR	acetylation	[1]
159	GAKHRISKEEAMRWF	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Required for rRNA maturation and formation of the 60S ribosomal subunits (By similarity). Binds to 5S ribosomal RNA. Promotes nucleolar location of PML (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 44 44 Phosphothreonine (By similarity).
 MOD_RES 52 52 N6-acetyllysine (By similarity).
 MOD_RES 85 85 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 178 AA 

Protein Sequence

Gene Ontology

 GO:0005730; C:nucleolus; ISS:UniProtKB.
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0034504; P:protein localization to nucleus; ISS:UniProtKB.
 GO:0006412; P:translation; IEA:InterPro. 

Interpro

 IPR002132; Ribosomal_L5.
 IPR020929; Ribosomal_L5_CS.
 IPR022803; Ribosomal_L5_domain. 

Pfam

 PF00281; Ribosomal_L5
 PF00673; Ribosomal_L5_C 

SMART

  

PROSITE

 PS00358; RIBOSOMAL_L5 

PRINTS