CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043567
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Chromodomain-helicase-DNA-binding protein 9 
Protein Synonyms/Alias
  
Gene Name
 CHD9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
264ATEEQLLKDKRIQQKmethylation[1]
534RLKNKNCKLLEGLKLubiquitination[2]
Reference
 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1099 AA 
Protein Sequence
MSSVKRPRGR PPSSKKSDGS GTYTKLQNTQ VRVMSEKKQR KKVESESKQE KANRIISEAI 60
AKAKERGERN IPRVMSPENF PTASVEGKEE KKGRRMKSKP KDKDSKKTKT CSKLKEKTKI 120
GKLIITLGKK QKRKNESSDE ISDAEQMPQH TLKDQDSQKR RSNRQIKRKK YAEDIEGKQS 180
EEEVKGSMKI KKNSAPLPGE QPLQLFVENP SEEDAAIVDK ILSSRTVKKE ISPGVMIDTE 240
EFFVKYKNYS YLHCEWATEE QLLKDKRIQQ KIKRFKLRQA QRAHFFADME EEPFNPDYVE 300
VDRVLEVSFC EDKDTGEPVI YYLVKWCSLP YEDSTWELKE DVDLAKIEEF EQLQASRPDT 360
RRLDRPPSNI WKKIDQSRDY KNGNQLREYQ LEGLNWLLFN WYNRRNCILA DEMGLGKTIQ 420
SITFLYEILL TGIRGPFLII APLSTIANWE REFRTWTDIN VVVYHGSLIS RQMIQQYEMY 480
FRDSQGRIIR GAYRFQAIIT TFEMILGGCG ELNAIEWRCV IIDEAHRLKN KNCKLLEGLK 540
LMNLEHKVLL TGTPLQNTVE ELFSLLHFLE PLRFPSESTF MQEFGDLKTE EQVQKLQAIL 600
KPMMLRRLKE DVEKKLAPKE ETIIEVELTN IQKKYYRAIL EKNFSFLSKG AGQTNVPNLV 660
NTMMELRKCC NHPYLIKGAE EKILGEFRDT YNPAASDFHL QAMIQSAGKL VLIDKLLPKM 720
KAGGHKVLIF SQMVRCLDIL EDYLIHKRYL YERIDGRVRG NLRQAAIDRF SKPDSDRFVF 780
LLCTRAGGLG INLTAADTCI IFDSDWNPQN DLQAQARCHR IGQNKAVKVY RLVTRNSYER 840
EMFDRASLKL GLDKAVLQSM SGRESNVGGI QQLSKKEIED LLRRGAYGAI MEEEDEGSKF 900
CEEDIDQILL RRTKTITIES EGRGSTFAKA SFVASGNRTD ISLDDPNFWQ KWAKKAEIDI 960
EAISGRNSLV IDTPRIRKQT RPFSATKDEL AELSEAESEG DEKPKLRRPC DRSNGYGRTE 1020
CFRVEKNLLV YGWGRWREIL SHGRFKRQLN EHDVEIICRA LLAYCLVHYR GDEKIKGFIW 1080
DLITPTEDGQ TRELQNHLG 1099 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0004386; F:helicase activity; IEA:InterPro. 
Interpro
 IPR017956; AT_hook_DNA-bd_motif.
 IPR023780; Chromo_domain.
 IPR000953; Chromo_domain/shadow.
 IPR016197; Chromodomain-like.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR000330; SNF2_N. 
Pfam
 PF00385; Chromo
 PF00271; Helicase_C
 PF00176; SNF2_N 
SMART
 SM00384; AT_hook
 SM00298; CHROMO
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS50013; CHROMO_2
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER 
PRINTS