Tag | Content |
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CPLM ID | CPLM-010968 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | SAP30-binding protein |
Protein Synonyms/Alias | Transcriptional regulator protein HCNGP |
Gene Name | Sap30bp |
Gene Synonyms/Alias | Hcngp |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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144 | KLYERKIKEGMDMNY | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival (By similarity). May be involved in the regulation of beta-2-microglobulin genes. |
Sequence Annotation | MOD_RES 18 18 Phosphoserine (By similarity). MOD_RES 22 22 Phosphoserine (By similarity). MOD_RES 43 43 Phosphoserine (By similarity). MOD_RES 52 52 Phosphoserine (By similarity). MOD_RES 113 113 Phosphoserine (By similarity). |
Keyword | Apoptosis; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 308 AA |
Protein Sequence | MAGKKNVLSS LAIYAEYSDP ESDGETGVDA VGGATEEKGG LVSDAYGEDD FSRPGGDEDG 60 YEEEEDENSK QSEDDDSETE KPEADDPKDN TEAEKRDPQE LVASFSERVR NMSPDEIKIP 120 PEPPGRCSNH LQDKIQKLYE RKIKEGMDMN YIIQRKKEFR NPSIYEKLIQ FCAIDELGTN 180 YPKDMFDPHG WSEDSYYEAL AKAQKIEMDK LEKAKKERTK IEFVTGTKKG TTTNATATST 240 STASTAVADA QKRKSKWDSA IPVTTIAQPT ILTTTATLPA VVTVTTSASG SKTTVISAVG 300 TIVKKAKQ 308 |
Gene Ontology | GO:0045111; C:intermediate filament cytoskeleton; IEA:Compara. GO:0005634; C:nucleus; ISS:UniProtKB. GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. GO:0006917; P:induction of apoptosis; ISS:UniProtKB. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
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