| Tag | Content |
|---|
| CPLM ID | CPLM-011068 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Mitochondrial-processing peptidase subunit beta |
Protein Synonyms/Alias | Beta-MPP; P-52 |
Gene Name | Pmpcb |
Gene Synonyms/Alias | Mppb |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 219 | LGPTENIKSISRKDL | acetylation | [1] | | 235 | DYITTHYKGPRIVLA | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Cleaves presequences (transit peptides) from mitochondrial protein precursors. |
Sequence Annotation | ACT_SITE 104 104 Proton acceptor (By similarity).
METAL 101 101 Zinc (By similarity).
METAL 105 105 Zinc (By similarity).
METAL 181 181 Zinc (By similarity). |
Keyword | Complete proteome; Direct protein sequencing; Hydrolase; Metal-binding; Metalloprotease; Mitochondrion; Protease; Reference proteome; Transit peptide; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 489 AA |
Protein Sequence | MAAAAVSRTL LPVAGRRLWG FTRRLPLRAA AAQPLYFGGD RLRSTQAAPQ VVLNVPETQV 60
TCLENGLRVA SENSGISTCT VGLWIDAGSR YENEKNNGTA HFLEHMAFKG TKKRSQLDLE 120
LEIENMGAHL NAYTSREQTV YYAKAFSKDL PRAVEILADI IQNSTLGEAE IERERGVILR 180
EMQEVETNLQ EVVFDYLHAT AYQNTALGRT ILGPTENIKS ISRKDLVDYI TTHYKGPRIV 240
LAAAGGVCHN ELLELAKFHF GDSLCAHKGD VPALPPCKFT GSEIRVRDDK MPLAHLAVAI 300
EAVGWTHPDT ICLMVANTLI GNWDRSFGGG MNLSSKLAQL TCHGNLCHSF QSFNTSYTDT 360
GLWGLYMVCE QATVADMLHA VQKEWMRLCT AVSESEVARA KNLLKTNMLL QLDGSTPICE 420
DIGRQMLCYN RRIPIPELEA RIDAVDAEMV REVCTKYIYG KSPAIAALGP IERLPDFNQI 480
CSNMRWTRD 489 |
Gene Ontology | GO:0005743; C:mitochondrial inner membrane; IEA:Compara. GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. GO:0005739; C:mitochondrion; IDA:RGD. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. GO:0006627; P:protein processing involved in protein targeting to mitochondrion; TAS:RGD. GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |