| Tag | Content |
|---|
| CPLM ID | CPLM-020977 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pre-mRNA-processing factor 17 |
Protein Synonyms/Alias | Cell division cycle 40 homolog; PRP17 homolog |
Gene Name | Cdc40 |
Gene Synonyms/Alias | Prp17; Prpf17 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 226 | ITAKRQKKGKQEEEK | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing (By similarity). |
Sequence Annotation | REPEAT 286 326 WD 1.
REPEAT 330 369 WD 2.
REPEAT 371 413 WD 3.
REPEAT 416 455 WD 4.
REPEAT 459 498 WD 5.
REPEAT 504 545 WD 6.
REPEAT 548 578 WD 7.
MOD_RES 187 187 Phosphoserine. |
Keyword | Complete proteome; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Spliceosome; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 579 AA |
Protein Sequence | MSAAIAALAA SYGSGSGSES DSDSEGSRCP LPAADSLMHL TKSPSAKLSL TVAVDSAPEV 60
AVKEDLETGV HLDPAVKEVQ YNPTYETMFA PEFGPENPFR TQQMAAPRNM LSGYAEPAHI 120
NDFMFEQQRR TFATYGYALD PSLDNHQVSA KYIGSVEEAE KNQGLTVFET GQKKTEKRKK 180
FKENDASNID GFLGPWAKYV DEKDVAKPSE EEQKELDEIT AKRQKKGKQE EEKPGEEKTI 240
LHVKEMYDYQ GRSYLHIPQD VGVNLRSSVP PEKCYLPKKQ IHVWSGHTKG VSAVRLFPLS 300
GHLLLSCSMD CKIKLWEVYG DRRCLRTFIG HSKAVRDICF NTAGTQFLSA AYDRYLKLWD 360
TETGQCISRF TNRKVPYCVK FNPDEDKQNL FVAGMSDKKI VQWDIRSGEI VQEYDRHLGA 420
VNTIVFVDEN RRFVSTSDDK SLRVWEWDIP VDFKYIAEPS MHSMPAVTLS PNGKWLACQS 480
MDNQILIFGA QNRFRLNKKK IFKGHMVAGY ACQVDFSPDM SYVISGDGNG KLNIWDWKTT 540
KLYSRFKAHD KVCIGAVWHP HETSKVITCG WDGLIKLWD 579 |
Gene Ontology | GO:0071013; C:catalytic step 2 spliceosome; IEA:Compara. GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |