CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021915
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription factor LAF1 
Protein Synonyms/Alias
 Myb-related protein 18; AtMYB18; Protein LONG AFTER FAR-RED LIGHT 1 
Gene Name
 LAF1 
Gene Synonyms/Alias
 MYB18; At4g25560; M7J2.70 
Created Date
 July 27, 2013 
Organism
 Arabidopsis thaliana (Mouse-ear cress) 
NCBI Taxa ID
 3702 
Lysine Modification
Position
Peptide
Type
References
258VFGSKCKKQEHHIYRsumoylation[1]
Reference
 [1] LAF1, a MYB transcription activator for phytochrome A signaling.
 Ballesteros ML, Bolle C, Lois LM, Moore JM, Vielle-Calzada JP, Grossniklaus U, Chua NH.
 Genes Dev. 2001 Oct 1;15(19):2613-25. [PMID: 11581165
Functional Description
 Transcription factor that promotes photomorphogenesis in the light by participating in the transmission of phytochrome A (phyA) signals to downstream responses. Probably acts by activating expression of light-induced genes. In darkness, its degradation prevents the activation of light-induced genes. 
Sequence Annotation
 DOMAIN 7 59 HTH myb-type 1.
 DOMAIN 60 114 HTH myb-type 2.
 DNA_BIND 35 59 H-T-H motif (By similarity).
 DNA_BIND 87 110 H-T-H motif (By similarity).  
Keyword
 Activator; Complete proteome; DNA-binding; Nucleus; Phytochrome signaling pathway; Reference proteome; Repeat; Transcription; Transcription regulation; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 283 AA 
Protein Sequence
MAKTKYGERH RKGLWSPEED EKLRSFILSY GHSCWTTVPI KAGLQRNGKS CRLRWINYLR 60
PGLKRDMISA EEEETILTFH SSLGNKWSQI AKFLPGRTDN EIKNYWHSHL KKKWLKSQSL 120
QDAKSISPPS SSSSSLVACG KRNPETLISN HVFSFQRLLE NKSSSPSQES NGNNSHQCSS 180
APEIPRLFFS EWLSSSYPHT DYSSEFTDSK HSQAPNVEET LSAYEEMGDV DQFHYNEMMI 240
NNSNWTLNDI VFGSKCKKQE HHIYREASDC NSSAEFFSPS TTT 283 
Gene Ontology
 GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IDA:TAIR.
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:TAIR.
 GO:0010018; P:far-red light signaling pathway; IMP:TAIR.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:TAIR.
 GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
 GO:0009751; P:response to salicylic acid stimulus; IEP:TAIR.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR009057; Homeodomain-like.
 IPR017930; Myb_dom.
 IPR001005; SANT/Myb. 
Pfam
 PF00249; Myb_DNA-binding 
SMART
 SM00717; SANT 
PROSITE
 PS51294; HTH_MYB 
PRINTS