| Tag | Content |
|---|
| CPLM ID | CPLM-009819 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | HTH-type transcriptional activator AaeR |
Protein Synonyms/Alias | |
Gene Name | aaeR |
Gene Synonyms/Alias | yhcS; b3243; JW3212 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 274 | VYALYTEKDKLPLKV | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Activates transcription of the aaeXAB operon. |
Sequence Annotation | DOMAIN 1 59 HTH lysR-type.
DNA_BIND 19 38 H-T-H motif (Potential). |
Keyword | Activator; Complete proteome; DNA-binding; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 309 AA |
Protein Sequence | MERLKRMSVF AKVVEFGSFT AAARQLQMSV SSISQTVSKL EDELQVKLLN RSTRSIGLTE 60
AGRIYYQGCR RMLHEVQDVH EQLYAFNNTP IGTLRIGCSS TMAQNVLAGL TAKMLKEYPG 120
LSVNLVTGIP APDLIADGLD VVIRVGALQD SSLFSRRLGA MPMVVCAAKS YLTQYGIPEK 180
PADLSSHSWL EYSVRPDNEF ELIAPEGIST RLIPQGRFVT NDPMTLVRWL TAGAGIAYVP 240
LMWVINEINR GELEILLPRY QSDPRPVYAL YTEKDKLPLK VQVVINSLTD YFVEVGKLFQ 300
EMHGRGKEK 309 |
Gene Ontology | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0006352; P:DNA-dependent transcription, initiation; IMP:EcoliWiki. GO:0006355; P:regulation of transcription, DNA-dependent; IMP:EcoliWiki. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |