CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037088
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 39S ribosomal protein L3, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 MRPL3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
71FVRGLHGKSGTWWDEubiquitination[1]
89EENVPFIKQLVSDEDubiquitination[1, 2]
184KTVSRFRKATSILEFubiquitination[3]
240VTAKTIGKGFQGVMKubiquitination[3]
287PGTKMPGKMGNIYRTubiquitination[3]
335DSKLPAYKDLGKNLPubiquitination[3, 4]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 375 AA 
Protein Sequence
MPGWRLLTQV GAQVLGRLGD GLGAALGPGN RVTTNSLNVS LIRRNVGSEE KVGDLKKRTH 60
IWLFVRGLHG KSGTWWDEHL SEENVPFIKQ LVSDEDKAQL ASKLCPLKDE PWPIHPWEPG 120
SFRVGLIALK LGMMPLWTKD GQKHVVTLLQ VQDCHVLKYT SKENCNGKMA TLSVGGKTVS 180
RFRKATSILE FYRELGLPPK QTVKIFNITD NAAIKPGTPL YAAHFRPGQY VDVTAKTIGK 240
GFQGVMKRWG FKGQPATHGQ TKTHRRPGAV ATGDIGRVWP GTKMPGKMGN IYRTEYGLKV 300
WRINTKHNII YVNGSVPGHK NCLVKVKDSK LPAYKDLGKN LPFPTYFPDG DEEELPEDLY 360
DENVCQPGAP SITFA 375 
Gene Ontology
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR000597; Ribosomal_L3.
 IPR019927; Ribosomal_L3_bac/org-type.
 IPR019926; Ribosomal_L3_CS.
 IPR009000; Transl_elong_init/rib_B-barrel. 
Pfam
 PF00297; Ribosomal_L3 
SMART
  
PROSITE
 PS00474; RIBOSOMAL_L3 
PRINTS