UniProt Accession

 FKBX_ECOLI; P0AEM0; P22563 

Genbank Protein ID

 X54945; U00096; AP009048 

Genbank Nucleotide ID

 CAA38706.1; AAC73139.1; BAB96597.1 

Protein Name

 FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase 

Protein Synonyms/Alias

 PPIase; Rotamase 

Gene Name

 fkpB 

Gene Synonyms/Alias

 slpA; yaaD; b0028; JW0026 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
33	ESTRNNGKPALFRLG	acetylation	[1]
56	EQHLLGLKVGDKTTF	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 PPIases accelerate the folding of proteins. Substrate specificity investigated with 'Suc-Ala-Xaa-Pro-Phe-4-nitroanilide' where Xaa is the amino acid tested, was found to be Phe > Leu >> Ile > Lys = Ala > Trp > His >> Gln. 

Sequence Annotation

 DOMAIN 2 72 PPIase FKBP-type.  

Keyword

 3D-structure; Complete proteome; Isomerase; Reference proteome; Rotamase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 149 AA 

Protein Sequence

Gene Ontology

 GO:0016020; C:membrane; ISS:RefGenome.
 GO:0005528; F:FK506 binding; ISS:RefGenome.
 GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:EcoCyc.
 GO:0006457; P:protein folding; IEA:UniProtKB-KW. 

Interpro

 IPR023566; PPIase_FKBP.
 IPR001179; PPIase_FKBP_dom. 

Pfam

 PF00254; FKBP_C 

SMART

  

PROSITE

 PS50059; FKBP_PPIASE 

PRINTS