UniProt Accession

 MUP1_MOUSE; P11588; Q61921 

Genbank Protein ID

 M16355; M28649; BC012221 

Genbank Nucleotide ID

 AAA39767.1; AAA39764.1; AAH12221.1 

Protein Name

 Major urinary protein 1 

Protein Synonyms/Alias

 MUP 1 

Gene Name

 Mup1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
158	RFAQLCEKHGILREN	acetylation	[1]

Reference

 [1] Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
 Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y.
 Mol Cell. 2006 Aug;23(4):607-18. [PMID: 16916647] 

Functional Description

 Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females. 

Sequence Annotation

 MOD_RES 158 158 N6-acetyllysine.
 DISULFID 82 175  

Keyword

 3D-structure; Acetylation; Complete proteome; Disulfide bond; Pheromone-binding; Reference proteome; Secreted; Signal; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 180 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0005615; C:extracellular space; IDA:UniProtKB.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0005009; F:insulin-activated receptor activity; IDA:UniProtKB.
 GO:0005550; F:pheromone binding; IDA:UniProtKB.
 GO:0036094; F:small molecule binding; IEA:InterPro.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0009060; P:aerobic respiration; IDA:UniProtKB.
 GO:0071240; P:cellular response to food; IEP:UniProtKB.
 GO:0009267; P:cellular response to starvation; IEP:UniProtKB.
 GO:0071394; P:cellular response to testosterone stimulus; IEP:UniProtKB.
 GO:0006112; P:energy reserve metabolic process; IDA:UniProtKB.
 GO:0042593; P:glucose homeostasis; IMP:UniProtKB.
 GO:0031649; P:heat generation; IDA:UniProtKB.
 GO:0045475; P:locomotor rhythm; IDA:UniProtKB.
 GO:0070584; P:mitochondrion morphogenesis; IDA:UniProtKB.
 GO:0045721; P:negative regulation of gluconeogenesis; IDA:UniProtKB.
 GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; IDA:UniProtKB.
 GO:0051055; P:negative regulation of lipid biosynthetic process; IDA:UniProtKB.
 GO:0010888; P:negative regulation of lipid storage; IDA:UniProtKB.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.
 GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
 GO:0010907; P:positive regulation of glucose metabolic process; IDA:UniProtKB.
 GO:0045834; P:positive regulation of lipid metabolic process; IDA:UniProtKB.
 GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.
 GO:0035634; P:response to stilbenoid; IEP:UniProtKB. 

Interpro

 IPR012674; Calycin.
 IPR011038; Calycin-like.
 IPR002345; Lipocalin.
 IPR022272; Lipocalin_CS.
 IPR000566; Lipocln_cytosolic_FA-bd_dom.
 IPR002971; Maj_urinary. 

Pfam

 PF00061; Lipocalin 

SMART

  

PROSITE

 PS00213; LIPOCALIN 

PRINTS

 PR00179; LIPOCALIN.
 PR01221; MAJORURINARY.