CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017430
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Melanoregulin 
Protein Synonyms/Alias
 Dilute suppressor protein homolog 
Gene Name
 MREG 
Gene Synonyms/Alias
 DSU; HDCGA21P 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
27EERALPEKEPLVSDNubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (By similarity). 
Sequence Annotation
 MOD_RES 213 213 Phosphoserine.  
Keyword
 Alternative splicing; Cell membrane; Complete proteome; Membrane; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 214 AA 
Protein Sequence
MGLRDWLRTV CCCCGCECLE ERALPEKEPL VSDNNPYSSF GATLVRDDEK NLWSMPHDVS 60
HTEADDDRTL YNLIVIRNQQ AKDSEEWQKL NYDIHTLRQV RREVRNRWKC ILEDLGFQKE 120
ADSLLSVTKL STISDSKNTR KAREMLLKLA EETNIFPTSW ELSERYLFVV DRLIALDAAE 180
EFFKLARRTY PKKPGVPCLA DGQKELHYLP FPSP 214 
Gene Ontology
 GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.
 GO:0042640; P:anagen; IEA:Compara.
 GO:0030318; P:melanocyte differentiation; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS