CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032694
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hexokinase, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_080890 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
110KMEIIQDKICLRSAEacetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Glycolysis; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 468 AA 
Protein Sequence
MQPRQPGDEA KQLAELEVVR KMMTPTREVL LELHESFLKE LQRGLEMHKR HGITWVPEEC 60
SMKMLDSCVS NLPTGAEVGE AYAIDFGGST CRAVRCSLLG KGKMEIIQDK ICLRSAEHRC 120
AKGFMDKKAG GKELFDQFAM CIRGLMDRSG DLKKAEETNT PVPVGFTFSF PCAQAALNSS 180
FLIEWTKGFE TGRENPDRVE GKDVAVLLAD ALQRHNVPAV CKAIVNDTVG TLVSCAYQRV 240
PGTPECRVGL IIGTGFNACY VEPEASNYGY TGTVVNMEAG NFHKDLPRNE IDVEVDEKTH 300
NRGKQQFEKL VSGYYIGEIV RVAAVRVFGA RAPEKASVRH SIHGETASTI RDDHSQDKAA 360
SIQAIKECWG VTMDLDDIKC IWEICRLVFD RSAAFAATLA VALCYRTGRL DTGSTVGIDG 420
ALYVKNQWYR EAVEYYTKLV AGDAAKNIHY CIADDGSGKG AALIADVN 468 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004396; F:hexokinase activity; IEA:EC.
 GO:0006096; P:glycolysis; IEA:UniProtKB-KW. 
Interpro
 IPR001312; Hexokinase.
 IPR022673; Hexokinase_C.
 IPR019807; Hexokinase_CS.
 IPR022672; Hexokinase_N. 
Pfam
 PF00349; Hexokinase_1
 PF03727; Hexokinase_2 
SMART
  
PROSITE
 PS00378; HEXOKINASES 
PRINTS
 PR00475; HEXOKINASE.