| Tag | Content |
|---|
| CPLM ID | CPLM-020289 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Chitinase domain-containing protein 1 |
Protein Synonyms/Alias | Stabilin-1-interacting chitinase-like protein; SI-CLP |
Gene Name | CHID1 |
Gene Synonyms/Alias | GL008; PSEC0104; SB139 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 127 | VTKVFGSKFTQISPV | ubiquitination | [1] | | 139 | SPVWLQLKRRGREMF | ubiquitination | [1] | | 315 | QVLDPKSKWRSKILL | ubiquitination | [1] | | 351 | ARYIQTLKDHRPRMV | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro). |
Sequence Annotation | |
Keyword | 3D-structure; Alternative splicing; Complete proteome; Immunity; Innate immunity; Lysosome; Polymorphism; Reference proteome; Secreted; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 393 AA |
Protein Sequence | MRTLFNLLWL ALACSPVHTT LSKSDAKKAA SKTLLEKVKF CSCCPGWSAM ARSWLTATSA 60
TQSQFSDKPV QDRGLVVTDL KAESVVLEHR SYCSAKARDR HFAGDVLGYV TPWNSHGYDV 120
TKVFGSKFTQ ISPVWLQLKR RGREMFEVTG LHDVDQGWMR AVRKHAKGLH IVPRLLFEDW 180
TYDDFRNVLD SEDEIEELSK TVVQVAKNQH FDGFVVEVWN QLLSQKRVGL IHMLTHLAEA 240
LHQARLLALL VIPPAITPGT DQLGMFTHKE FEQLAPVLDG FSLMTYDYST AHQPGPNAPL 300
SWVRACVQVL DPKSKWRSKI LLGLNFYGMD YATSKDAREP VVGARYIQTL KDHRPRMVWD 360
SQASEHFFEY KKSRSGRHVV FYPTLKSLQV RLELARELGV GVSIWELGQG LDYFYDLL 418 |
Gene Ontology | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. GO:0004568; F:chitinase activity; IEA:InterPro. GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. GO:0006032; P:chitin catabolic process; IEA:InterPro. GO:0045087; P:innate immune response; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |