CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004628
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoserine phosphatase RsbX 
Protein Synonyms/Alias
 Sigma-B negative effector 
Gene Name
 rsbX 
Gene Synonyms/Alias
 BSU04740 
Created Date
 July 27, 2013 
Organism
 Bacillus subtilis (strain 168) 
NCBI Taxa ID
 224308 
Lysine Modification
Position
Peptide
Type
References
36FFMKADDKELICAVAacetylation[1]
Reference
 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065
Functional Description
 Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels. 
Sequence Annotation
 DOMAIN 22 199 PP2C-like.  
Keyword
 Complete proteome; Hydrolase; Protein phosphatase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 199 AA 
Protein Sequence
MIQVEENEHI QTLVYQLNKE GKSICGDSFF MKADDKELIC AVADGLGSGS LANESSAAIK 60
DLVENYASED VESIIERCNQ AMKNKRGATA SILKINFEQR QFTYCSVGNV RFILHSPSGE 120
SFYPLPISGY LSGKPQKYKT HTATYEKGSK FIIHTDGLNV PDIRSHLKKG QSVEEISNSL 180
KMYTTSRKDD LTYILGQLS 199 
Gene Ontology
 GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
 GO:0004647; F:phosphoserine phosphatase activity; IEA:EC.
 GO:0008152; P:metabolic process; IEA:GOC. 
Interpro
 IPR001932; PP2C-like. 
Pfam
 PF07228; SpoIIE 
SMART
 SM00331; PP2C_SIG
 SM00332; PP2Cc 
PROSITE
  
PRINTS