CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034637
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Chd7 
Protein Synonyms/Alias
  
Gene Name
 Chd7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
609DPSKGFGKDDFPGGVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2985 AA 
Protein Sequence
MADPGMMSLF GEDGNIFSEG LEGLGECGYP ENPVNPMGQQ MPIDQGFPSL QPSLHHPSPN 60
QNQTKLTHFD HYNQYEQKMH LMDQPNRMMG SAPGNGLASP HSQYHTPPVP QVPHGGGSGG 120
GQMGVYPGMQ NDRHGQSFVD GGSMWGPRAV QVPDQIRAPY QQQQPQPAPS GPPAQGHPQH 180
MQQMGSYLAR GDFSMQQPQQ RMSQFSQGQE GLSQGSPFIA TSGPGGHLSH MPQQSPNIAP 240
SLRHPVQQQF HHHPAALHGE SVAHSPRFSP NPPQQGAVRP QTLNFSSRSQ TVPSPTVNNS 300
GQYSPYPYRN LNQGLVNSTG MNQNLGLTNS TPMNQSVPRY PNAVGFPSNS GQGLMLQQPI 360
HSSGSLNQMN TQTMHPSQPQ GTYASPPPMS PMKAMSNPAG TPPPQVRPGS AGIPMDVGSY 420
PNMPHPQPSH QPPGAMGIGQ RNMGPRNIQQ PRPFMGMSST PRELTGHMRP NGCPGVGLAD 480
AQAIQERLIP GQQHPGQQPP FQQLPTCPPL QPHPGLHQSS PPHPHHQPWA QLHPSPQNTP 540
QKVPVRQHSP SEPFLEKPVP DMTQVSGQNA QLVKSDDYLP SIEQQPQQKK KKKKNNHIAA 600
GDPSKGFGKD DFPGGVDNQE LSRNSLDASQ EETKKRKRPK VKKDPKELKE PREKKEPKTP 660
KAPKTPKEPK ERKAKTVTPK PKSSKKSSNK KPDSEASALK KKVNKGKTEG SENSDLDKTP 720
PPSPGPEEDE DPGVQKRRSS RQVKRKRYTE DLEFKISDEE ADDADAAGRD SPSNTSQSEQ 780
QESVDAEGPV VEKIMSSRLV KKQKESGEEV EVEEFYVKYK NFSYLHCQWA SVEDLEKDKR 840
IQQKIKRFKS KQGQSKFLSE IEDDLFNPDY VEVDRIMDFA RSTDDRGEPV THYLVKWCSL 900
PYEDSTWELR QDLDQAKIEE FEKLMSREPE TERVERPPAD DWKKSESSRE YKNNNKLREY 960
QLEGVNWLLF NWYNMRNCIL ADEMGLGKTI QSITFLYEIY LKGIHGPFLV IAPLSTIPNW 1020
EREFRTWTEL NVVVYHGSQA SRRTIQLYEM YFKDPQGRVI KGSYKFHAII TTFEMILTDC 1080
PELRNIPWRC VVIDEAHRLK NRNCKLLEGL KMMDLEHKVL LTGTPLQNTV EELFSLLHFL 1140
EPSRFPSETT FMQEFGDLKT EEQVQKLQAI LKPMMLRRLK EDVEKNLAPK EETIIEVELT 1200
NIQKKYYRAI LEKNFTFLSK GGGQANVPNL LNTMMELRKC CNHPYLINGA EEKILEEFKD 1260
AHNADSPDFQ LQAMIQAAGK LVLIDKLLPK LKAGGHRVLI FSQMVRCLDI LEDYLIQRRY 1320
PYERIDGRVR GNLRQAAIDR FSKPDSDRFV FLLCTRAGGL GINLTAADTC IIFDSDWNPQ 1380
NDLQAQARCH RIGQSKSVKI YRLITRNSYE REMFDKASLK LGLDKAVLQS MSGRENATNG 1440
VQQLSKKEIE DLLRKGAYGA LMDEEDEGSK FCEEDIDQIL LRRTHTITIE SEGKGSTFAK 1500
ASFVASGNRT DISLDDPNFW QKWAKKAELD IDALNGRNNL VIDTPRVRKQ TRLYSAVKED 1560
ELMEFSDLES DSEEKPCIKP RRPQDKTQGY ARSECFRVEK NLLVYGWGRW TDILSHGRYK 1620
RQLTEHDVET ICRAILVYCL NHYRGDENIK SFIWDLITPT ADGQTRALLN HSGLSAPVPR 1680
GRKGKKVKAQ SMQPVVQDAD WLASCNPDAL FQEDSYKKHL KHHCNKVLLR VRMLYYLRQE 1740
VIGDQAEKIL EGADSSEADV WIPEPFHAEV PADWWDKEAD KSLLIGVFKH GYEKYNSMRA 1800
DPALCFLERV GMPDAKAIAA EQRGTDMLAD GGDGGEFDRE DEDPEYKPTR APFKDEIDEF 1860
ANSPPEDKED SMEAQSTGKH SESNAELGQL YWPNTSSLTT RLRRLITAYQ RSYKRQQMRQ 1920
EALMKTDRRR RRPREEVRAL EAEREAIISE KRQKWTRREE ADFYRVVSTF GVIFDPVKQQ 1980
FDWNQFRAFA RLDKKSDESL EKYFSCFVAM CRRVCRMPAK PEDEPPDLAS LIEPITEERA 2040
SRTLYRIELL RKIREQVLHH PQLSDRLKLC QPSLDLPEWW ECGRHDRDLL VGAAKHGVSR 2100
TDYHILNDPE LSFLDAHKSF AQNRGASTVP SLNTLAMGFG QAPPVIASAH AHEEKVMEQA 2160
EGKAEECEHS PAKERSDGKE EEEEAGGAKD SRQECEAEAS SVKGELKGVE GSGDPGSKSV 2220
SEKGSEEDEE EKLEDDDKSE ESSQPEAGAV SRGKTFDEES NASMSTARDE TRDGFYMEDG 2280
DPSVAQLLHE RTFAFSFWPK DRVMINRLDN ICEAVLKGKW PINRRQMFDF QGLVPGYPPS 2340
TVDSPLQKRS FAELSMVSQA SVSASEDITT SPQLSKDDAL NLSVPRQRRR RRRKVEIEAE 2400
RAAKRRNLME MVAQLRESQV VSENGQEKVV DLSKASREAT SSTSNFSSLT SKFILPNVST 2460
PVSDAFKTQM ELLQAGLSRT PTRHVLNGSL VDGEPPMKRR RGRRKNVEGL DLLFMSHKRT 2520
PLSAEDAEVT KAFEEDIETP PIRNIPSPGQ LDPDTRIPVI NLEDGTRLVG EEAPKNKDLV 2580
DWLKLHPMYT VDMPSYVPKN ADVLFSPFQK PKQKRHRCRN PNKLDINTLT GEERVPVVNK 2640
RNGKKMGGAM APPMKDLPRW LEENPEFAVA PDWTDIVKQS GFVPESMFDR LLTGPVVRGE 2700
GASRRGRRPK SEIARAAAAA AAVASTSGIN PLLVNSLFAG MDLTSLQNLQ NLQSLQLAGL 2760
MGFPPGLATA ATAGGDAKGP AAVLPLMLPG MAGLPNVFGL GGLLNNPLSA ATGNTTTASS 2820
QGEPEDGTSK AEEKGNDNED ENRDSEKSTD AVSAADSANG SVGAATAPAA LPSNPLAFNP 2880
FLLSTMAPGL FYPSMFLPPG LGGLTLPGFP ALAGLQNAVG ASEEKAADKA EGGPCKDGET 2940
LEGSDAEENL DKTIESSILE DEVAQGEELD SLEGGDEIEN NGNDE 2985 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0004386; F:helicase activity; IEA:InterPro.
 GO:0007512; P:adult heart development; IEA:Compara.
 GO:0007628; P:adult walking behavior; IEA:Compara.
 GO:0048844; P:artery morphogenesis; IEA:Compara.
 GO:0008015; P:blood circulation; IEA:Compara.
 GO:0007417; P:central nervous system development; IEA:Compara.
 GO:0050890; P:cognition; IEA:Compara.
 GO:0021545; P:cranial nerve development; IEA:Compara.
 GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Compara.
 GO:0060324; P:face development; IEA:Compara.
 GO:0030540; P:female genitalia development; IEA:Compara.
 GO:0003007; P:heart morphogenesis; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0043584; P:nose development; IEA:Compara.
 GO:0060021; P:palate development; IEA:Compara.
 GO:0040018; P:positive regulation of multicellular organism growth; IEA:Compara.
 GO:0060123; P:regulation of growth hormone secretion; IEA:Compara.
 GO:0060041; P:retina development in camera-type eye; IEA:Compara.
 GO:0048752; P:semicircular canal morphogenesis; IEA:Compara.
 GO:0007605; P:sensory perception of sound; IEA:Compara.
 GO:0001501; P:skeletal system development; IEA:Compara.
 GO:0030217; P:T cell differentiation; IEA:Compara. 
Interpro
 IPR006576; BRK_domain.
 IPR023780; Chromo_domain.
 IPR000953; Chromo_domain/shadow.
 IPR016197; Chromodomain-like.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR001005; SANT/Myb.
 IPR000330; SNF2_N. 
Pfam
 PF07533; BRK
 PF00385; Chromo
 PF00271; Helicase_C
 PF00176; SNF2_N 
SMART
 SM00592; BRK
 SM00298; CHROMO
 SM00487; DEXDc
 SM00490; HELICc
 SM00717; SANT 
PROSITE
 PS50013; CHROMO_2
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER 
PRINTS