Tag | Content |
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CPLM ID | CPLM-025822 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Myeloid/lymphoid or mixed-lineage leukemia 2 variant |
Protein Synonyms/Alias | |
Gene Name | |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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246 | LVESANEKAEREALL | acetylation | [1] |
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Reference | [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. Science. 2009 Aug 14;325(5942):834-40. [ PMID: 19608861] |
Functional Description | |
Sequence Annotation | |
Keyword | Methyltransferase; Nucleus; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 2704 AA |
Protein Sequence | SARFPSTPGP ELGRQALGSP LAGISTRLPG PGEPVPGPAG PAQFIELRHN VQKGLGPGGT 60 PFPGQGPPQR PRFYPVSEDP HRLAPEGLRG LAVSGLPPQK PSAPPAPELN NSLHPTPHTK 120 GPTLPTGLEL VNRPPSSTEL GRPNPLALEA GKLPCEDPEL DDDFDAHKAL EDDEELAHLG 180 LGVDVAKGDD ELGTLENLET NDPHLDDLLN GDEFDLLAYT DPELDTGDKK DIFNEHLRLV 240 ESANEKAERE ALLRGVEPGP LGPEERPPPA ADASEPRLAS VLPEVKPKVE EGGRHPSPCQ 300 FTIATPKVEP APAANSLGLG LKPGQSMMGS RDTRMGTGPF SSSGHTAEKA SFGATGGPPA 360 HLLTPSPLSG PGGSSLLEKF ELESGALTLP GGPAASGDEL DKMESSLVAS ELPLLIEDLL 420 EHEKKELQKK QQLSAQLQPA QQQQQQQQQH SLLSAPGPAQ AMSLPHEGSS PSLAGSQQQL 480 SLGLAGARQP GLPQPLMPTQ PPAHALQQRL APSMAMVSNQ GHMLSGQHGG QAGLVPQQSS 540 QPVLSQKPMG TMPPSMCMKP QQLAMQQQLA NSFFPDTDLD KFAAEDIIDP IAKAKMVALK 600 GIKKVMAQGS IGVAPGMNRQ QVSLLAQRLS GGPSSDLQNH VAAGSGQERS AGDPSQPRPN 660 PPTFAQGVIN EADQRQYEEW LFHTQQLLQM QLKVLEEQIG VHRKSRKALC AKQRTAKKAG 720 REFPEADAEK LKLVTEQQSK IQKQLDQVRK QQKEHTNLMA EYRNKQQQQQ QQQQQQQQQH 780 SAVLALSPSQ SPRLLTKLPG QLLPGHGLQP PQGPPGGQAG GLRLTPGGMA LPGQPGGPFL 840 NTALAQQQQQ QHSGGAGSLA GPSGGFFPGN LALRSLGPDS RLLQERQLQL QQQRMQLAQK 900 LQQQQQQQQQ QQHLLGQVAI QQQQQQGPGV QTNQALGPKP QGLMPPSSHQ GLLVQQLSPQ 960 PPQGPQGMLG PAQVAVLQQQ HPGALGPQGP HRQVLMTQSR VLSSPQLAQQ GQGLMGHRLV 1020 TAQQQQQQQQ HQQQGSMAGL SHLQQSLMSH SGQPKLSAQP MGSLQQLQQQ QQLQQQQQLQ 1080 QQQQQQLQQQ QQLQQQQLQQ QQQQQQLQQQ QQQQLQQQQQ QLQQQQQQQQ QQFQQQQQQQ 1140 QMGLLNQSRT LLSPQQQQQQ QVALGPGMPA KPLQHFSSPG ALGPTLLLTG KEQNTVDPAV 1200 SSEATEGPST HQGGPLAIGT TPESMATEPG EVKPSLSGDS QLLLVQPQPQ PQPSSLQLQP 1260 PLRLPGQQQQ QVSLLHTAGG GSHGQLGSGS SSEASSVPHL LAQPSVSLGD QPGSMTQNLL 1320 GPQQPMLERP MQNNTGPQPP KPGPVLQSGQ GLPGVGIMPT VGQLRAQLQG VLAKNPQLRH 1380 LSPQQQQQLQ ALLMQRQLQQ SQAVRQTPPY QEPGTQTSPL QGLLGCQPQL GGFPGPQTGP 1440 LQELGAGPRP QGPPRLPAPP GALSTGPVLG PVHPTPPPSS PQEPKRPSQL PSPSSQLPTE 1500 AQLPPTHPGT PKPQGPTLEP PPGRVSPAAA QLADTLFSKG LGPWDPPDNL AETQKPEQSS 1560 LVPGHLDQVN GQVVPEASQL SIKQEPREEP CALGAQSVKR EANGEPIGAP GTSNHLLLAG 1620 PRSEAGHLLL QKLLRAKNVQ LSTGRGSEGL RAEINGHIDS KLAGLEQKLQ GTPSNKEDAA 1680 ARKPLTPKPK RVQKASDRLV SSRKKLRKED GVRASEALLK QLKQELSLLP LTEPAITANF 1740 SLFAPFGSGC PVNGQSQLRG AFGSGALPTG PDYYSQLLTK NNLSNPPTPP SSLPPTPPPS 1800 VQQKMVNGVT PSEELGEHPK DAASARDSER ALRDTSEVKS LDLLAALPTP PHNQTEDVRM 1860 ESDEDSDSPD SIVPASSPES ILGEEAPRFP HLGSGRWEQE DRALSPVIPL IPRASIPVFP 1920 DTKPYGALGL EVPGKLPVTT WEKGKGSEVS VMLTVSAAAA KNLNGVMVAV AELLSMKIPN 1980 SYEVLFPESP ARAGTEPKKG EAEGPGGKEK GLEGKSPDTG PDWLKQFDAV LPGYTLKSQL 2040 DILSLLKQES PAPEPPTQHS YTYNVSNLDV RQLSAPPPEE PSPPPSPLAP SPASPPTEPL 2100 VELPTEPLAE PPVPSPLPLA SSPESARPKP RARPPEEGED SRPPRLKKWK GVRWKRLRLL 2160 LTIQKGSGRQ EDEREVAEFM EQLGTALRPD KVPRDMRRCC FCHEEGDGAT DGPARLLNLD 2220 LDLWVHLNCA LWSTEVYETQ GGALMNVEVA LHRGLLTKCS LCQRTGATSS CNRMRCPNVY 2280 HFACAIRAKC MFFKDKTMLC PMHKIKGPCE QELSSFAVFR RVYIERDEVK QIASIIQRGE 2340 RLHMFRVGGL VFHAIGQLLP HQMADFHSAT ALYPVGYEAT RIYWSLRTNN RRCCYRCSIG 2400 ENNGRPEFVI KVIEQGLEDL VFTDASPQAV WNRIIEPVAA MRKEADMLRL FPEYLKGEEL 2460 FGLTVHAVLR IAESLPGVES CQNYLFRYGR HPLMELPLMI NPTGCARSEP KILTHYKRPH 2520 TLNSTSMSKA YQSTFTGETN TPYSKQFVHS KSSQYRRLRT EWKNNVYLAR SRIQGLGLYA 2580 AKDLEKHTMV IEYIGTIIRN EVANRREKIY EEQNRGIYMF RINNEHVIDA TLTGGPARYI 2640 NHSCAPNCVA EVVTFDKEDK IIIISSRRIP KGEELTYDYQ FDFEDDQHKI PCHCGAWNCR 2700 KWMN 2704 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-KW. GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0001701; P:in utero embryonic development; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |