Tag | Content |
---|
CPLM ID | CPLM-004201 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Carbonic anhydrase 3 |
Protein Synonyms/Alias | Carbonate dehydratase III; Carbonic anhydrase III; CA-III |
Gene Name | Ca3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
---|
3 | *****MAKEWGYASH | acetylation | [1] | 24 | HELYPIAKGDNQSPI | acetylation | [1] | 36 | SPIELHTKDIRHDPS | acetylation | [1] | 57 | SYDPGSAKTILNNGK | acetylation | [1] | 126 | HLVHWNPKYNTFGEA | acetylation | [1] | 135 | NTFGEALKQPDGIAV | acetylation | [1] | 153 | FLKIGREKGEFQILL | acetylation | [1] | 165 | ILLDALDKIKTKGKE | acetylation | [1] | 167 | LDALDKIKTKGKEAP | acetylation | [1] | 224 | VSSDQMAKLRSLFAS | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Reversible hydration of carbon dioxide. A major participant in the liver response to oxidative stress. |
Sequence Annotation | REGION 64 67 Involved in proton transfer (By REGION 198 199 Substrate binding (By similarity). ACT_SITE 127 127 By similarity. METAL 94 94 Zinc; catalytic. METAL 96 96 Zinc; catalytic. METAL 119 119 Zinc; catalytic. MOD_RES 2 2 N-acetylalanine (By similarity). MOD_RES 182 182 S-glutathionyl cysteine. MOD_RES 187 187 S-glutathionyl cysteine. |
Keyword | 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Glutathionylation; Lyase; Metal-binding; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 260 AA |
Protein Sequence | MAKEWGYASH NGPEHWHELY PIAKGDNQSP IELHTKDIRH DPSLQPWSVS YDPGSAKTIL 60 NNGKTCRVVF DDTFDRSMLR GGPLSGPYRL RQFHLHWGSS DDHGSEHTVD GVKYAAELHL 120 VHWNPKYNTF GEALKQPDGI AVVGIFLKIG REKGEFQILL DALDKIKTKG KEAPFNHFDP 180 SCLFPACRDY WTYHGSFTTP PCEECIVWLL LKEPMTVSSD QMAKLRSLFA SAENEPPVPL 240 VGNWRPPQPI KGRVVRASFK 260 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |