CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030183
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA, FLJ93988, highly similar to Homo sapiens baculoviral IAP repeat-containing 2 (BIRC2), mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
36SDWTNSNKQKMKYDFubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 618 AA 
Protein Sequence
MHKTASQRLF PGPSYQNIKS IMEDSTILSD WTNSNKQKMK YDFSCELYRM STYSTFPAGV 60
PVSERSLARA GFYYTGVNDK VKRFCCGLML DNWKLGDSPI QKHKQLYPSC SFIQNLVSAS 120
LGSTSKNTSP MRNSFAHSLS PTLEHSSLFS GSYSSLPPNP LNSRAVEDIS SSRTNPYSYA 180
MSTEEARFLT YHMWPLTFLS PSELARAGFY YIGPGDRVAC FACGGKLSNW EPKDDAMSEH 240
RRHFPNCPFL ENSLETLRFS ISNLSMQTHA ARMRTFMYWP SSVPVQPEQL ASAGFYYVGR 300
NDDVKCFCCD GGLRCWESGD DPWVEHAKWF PRCEFLIRMK GQEFVDEIQG RYPHLLEQLL 360
STSDTTGEEN ADPPIIHFGP GESSSEDAVM MNTPVVKSAL EMGFNRDLVK QTVQSKILTT 420
GENYKTVNDI VSALLNAEDE KREEEKEKQA EEMASDDLSL IRKNRMALFQ QLTCVLPILD 480
NLLKANVINK QEHDIIKQKT QIPLQARELI DTILVKGNAA ANIFKNCLKE IDSTLYKNLF 540
VDKNMKYIPT EDVSGLSLEE QLRRLQEERT CKVCMDKEVS VVFIPCGHLV VCQECAPSLR 600
KCPICRGIIK GTVRTFLS 618 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0042981; P:regulation of apoptotic process; IEA:InterPro. 
Interpro
 IPR001370; BIR.
 IPR001315; CARD.
 IPR011029; DEATH-like_dom.
 IPR001841; Znf_RING. 
Pfam
 PF00653; BIR
 PF00619; CARD 
SMART
 SM00238; BIR
 SM00114; CARD
 SM00184; RING 
PROSITE
 PS01282; BIR_REPEAT_1
 PS50143; BIR_REPEAT_2
 PS50209; CARD
 PS50089; ZF_RING_2 
PRINTS