CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043287
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Histone acetyltransferase KAT8 
Protein Synonyms/Alias
  
Gene Name
 KAT8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
152STVGSPEKPLSDLGKacetylation[1, 2, 3]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 187 AA 
Protein Sequence
XYGKQPKLWL CEYCLKYMKY EKSYRFHLGQ CQWRQPPGKE IYRKSNISVY EVDGKDHKIY 60
CQNLCLLAKL FLDHKTLYFD VEPFVFYILT EVDRQGAHIV GYFSKEKESP DGNNVACILT 120
LPPYQRRGYG KFLIAFSYEL SKLESTVGSP EKPLSDLGKL SYRSYWSWVL LEILRDFRGT 180
LSIKDLR 187 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR002717; MOZ_SAS. 
Pfam
 PF01853; MOZ_SAS 
SMART
  
PROSITE
  
PRINTS