Tag | Content |
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CPLM ID | CPLM-018596 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Solute carrier organic anion transporter family member 1A5 |
Protein Synonyms/Alias | Organic anion-transporting polypeptide 3; OATP-3; Sodium-independent organic anion transporter 3; Solute carrier family 21 member 7 |
Gene Name | Slco1a5 |
Gene Synonyms/Alias | Oatp1a5; Oatp3; Slc21a7 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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667 | VENDGELKTKL**** | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Mediates the Na(+)-independent transport of organic anions such as taurocholate and thyroid hormones (By similarity). |
Sequence Annotation | DOMAIN 433 488 Kazal-like. CARBOHYD 124 124 N-linked (GlcNAc...) (Potential). CARBOHYD 135 135 N-linked (GlcNAc...) (Potential). CARBOHYD 483 483 N-linked (GlcNAc...) (Potential). CARBOHYD 492 492 N-linked (GlcNAc...) (Potential). DISULFID 439 465 By similarity. DISULFID 443 454 By similarity. DISULFID 445 469 By similarity. |
Keyword | Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 670 AA |
Protein Sequence | MGETEKRIAT HGVRCFSKIK MFLLALTCAY VSKSLSGIYM NSMLTQIERQ FDIPTSIVGL 60 INGSFEIGNL LLIILVSYFG TKLHRPIMIG IGCVIMGLGC FLMSLPHFLM GRYEYETTIS 120 PTSNLSSNSF LCMENRTQTL KPTQDPAECV KEMKSLMWIY VLVGNIIRGI GETPIMPLGI 180 SYIEDFAKSE NSPLYIGILE SGKMIGPIVG LLLGSFCARI YVDTGSVNTD DLTITPTDTR 240 WVGAWWIGFL VCAGVNILTS IPFFFFPKTL PKEGLQDNVA RTENDKEEKH REKAKEENRG 300 ITKDFLPFMK SLSCNPIYML LILTSVLQIN AFINMFTFLP KYLEQQYGKS TSEVVLLIGV 360 CNLPPICIGY LLIGFIMKKF RITVKKAAYM AFCLSLFEYL LSYFHFMISC DNFQVAGLTT 420 SYEGVQHPLY VENKVLADCN TRCSCLTNTW DPVCGDNGLS YMSACLAGCE KSVGMGTHMV 480 FQNCSCIQSS GNSSAVLGLC KKGPECANKL QYFLIMSVIG SFIYSITAIP GYMVLLRCIK 540 SEEKSLGIGL HAFCTRIFAG IPAPIYFGAL IDRTCLHWGT LKCGEPGACR IYNINNFRRI 600 YLVLPAALRG SSYLPAFFIL ILMRKFQLPG EMYSSETELA DMKQTVKKSE CTDVHGIPKV 660 ENDGELKTKL 670 |
Gene Ontology | GO:0031526; C:brush border membrane; IEA:Compara. GO:0005887; C:integral to plasma membrane; ISO:MGI. GO:0015125; F:bile acid transmembrane transporter activity; ISO:MGI. GO:0015349; F:thyroid hormone transmembrane transporter activity; IEA:Compara. GO:0050892; P:intestinal absorption; IEA:Compara. GO:0031100; P:organ regeneration; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |