CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007029
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cruciform DNA-recognizing protein 1 
Protein Synonyms/Alias
 CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide 
Gene Name
 CRP1 
Gene Synonyms/Alias
 YHR146W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
54MPVKLANKDDTFQFKacetylation[1]
54MPVKLANKDDTFQFKubiquitination[2]
270VESSVTEKSPALPQAubiquitination[2]
376PIVNKAPKLPLTDEQubiquitination[2]
436QTVKAPKKQTASPLSubiquitination[2]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Cruciform DNA-binding protein which exerts an enhancing effect on the cleavage of cruciform DNA (X-DNA) by endonuclease VII from bacteriophage T4. 
Sequence Annotation
 REGION 160 161 X-DNA-binding.
 MOD_RES 153 153 Phosphoserine.
 MOD_RES 156 156 Phosphoserine.
 MOD_RES 182 182 Phosphothreonine.
 MOD_RES 271 271 Phosphoserine.
 MOD_RES 295 295 Phosphothreonine.
 MOD_RES 319 319 Phosphoserine.
 MOD_RES 343 343 Phosphoserine.
 MOD_RES 366 366 Phosphothreonine.
 MOD_RES 394 394 Phosphoserine.
 MOD_RES 440 440 Phosphoserine.  
Keyword
 Complete proteome; DNA-binding; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 465 AA 
Protein Sequence
MSSELMFNYT FSWPAGPKDV ILTGTFDDWR GTLPLVKTAK GNFEITMPVK LANKDDTFQF 60
KFIVDGVWCV SDSYKKEHVS EGIENNFLQI TDLVETQEVA GASRIPEAGG LLCGKPPRSA 120
GPPSTSNRKK NKRNNKKRRS KLKKKSTKNN KKSNESLDDN EEEDGVTGTT TEDVTGTSRE 180
ETPLAEPTNV SKEAPGNFHI LPIDQSADTT QSNGIIGGPG PVLVPNPGEI KEFTEIRDVD 240
ARELNERLNK KEEVPEPVAG PIVESSVTEK SPALPQADDP IVETKEVAHN VQELTPQVEA 300
VTPLINEPEP LPTPEAQISI PESSKVEPVE GSLQSKLVEK RESTEGVLDG SKKVENKAKK 360
DEEVFTLDPI VNKAPKLPLT DEQTAEGRKS PAVSEEKEKK KKQEKGSKEV KRSETSKEKK 420
PSAKEVKKQT VKAPKKQTAS PLSSSTEEPK KKKTGFFGKL KKLFK 465 
Gene Ontology
 GO:0005634; C:nucleus; IC:SGD.
 GO:0003677; F:DNA binding; IDA:SGD. 
Interpro
  
Pfam
  
SMART
  
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PRINTS