CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030191
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BTB/POZ domain-containing protein KCTD14 
Protein Synonyms/Alias
 Potassium channel tetramerisation domain containing 14, isoform CRA_a; cDNA, FLJ94527 
Gene Name
 KCTD14 
Gene Synonyms/Alias
 hCG_26453 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
38EMFSSLAKASTDAEGubiquitination[1, 2, 3]
86EAQFYEIKPLVKLLEubiquitination[1, 3]
106FGEQVSRKQFLLQVPubiquitination[3]
209FYLTYPTKRNEFHFNacetylation[4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [4] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ion channel; Ion transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 225 AA 
Protein Sequence
MSTVVELNVG GEFHTTTLGT LRKFPGSKLA EMFSSLAKAS TDAEGRFFID RPSTYFRPIL 60
DYLRTGQVPT QHIPEVYREA QFYEIKPLVK LLEDMPQIFG EQVSRKQFLL QVPGYSENLE 120
LMVRLARAEA ITARKSSVLV CLVETEEQDA YYSEVLCFLQ DKKMFKSVVK FGPWKAVLDN 180
SDLMHCLEMD IKAQGYKVFS KFYLTYPTKR NEFHFNIYSF TFTWW 225 
Gene Ontology
 GO:0051260; P:protein homooligomerization; IEA:InterPro. 
Interpro
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR003131; T1-type_BTB. 
Pfam
 PF02214; K_tetra 
SMART
 SM00225; BTB 
PROSITE
  
PRINTS