CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032860
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Smarca-related protein 
Protein Synonyms/Alias
  
Gene Name
 PFF1185w 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
339LVDNVQLKPHQEDGVacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2719 AA 
Protein Sequence
MRIRKTWCTL CRENFEEGDE CIQCKQCKKK FHRECLQAEG LMDNEQLKDI KNYVCYQCIN 60
EDDDIPENED RCKICREKSA NLILLLCDGC PNSYHVSCLG LAAEPESEKW YCPICKPDDH 120
KNLDVRRMRK GFVLDNMNGE HVNSSTCYVC QRPGKLLGCD FCPNSFHPTC LPDLDFDNIS 180
DQWECPCCKN EDPLLNQGHK RWTKNEIQEI MKKRQRELGF WRSKIIKYRN RFLLAHRKDL 240
QPFVNPRVFS NLTKTFKNDY FHTKGSSNNK KSNKYDNDKY NSKKDVDMDS KEFNEFISSL 300
EDEAHQNACK FIESVFLSVY YPNGRKIERR PLVDNVQLKP HQEDGVEWLL KSFLTGGAIL 360
ADEMGLGKTI QTLCFLSYLK CNKIDGPHLI VVPLSTVGNW LREIHRFTPH LTCIKICGSK 420
NERTHAKEDR LAEKGLYDLY VTTYETVKNE EEFFVETIPK WQCIVLDEAH RIKNQSGAIR 480
HSMDRVVGNM RLLLTGTPLQ NNSAELFTLI NFMFPDIFKN SEIIEQAFMN ASQNNKNKSN 540
NNNNNNNKDE KNNNNDDDDD GGGGGGGANT SGNNTSKVNV NIGNIDLKSA IKEEDLKSIR 600
CLLDKIMLRR LKEQAITLPK KIFHDVWLPL GTLSAHWYKR LLDIRSMVEE KVSVKKLLGL 660
VIKMRIICGH PKGIVSRPSQ MEKLFAFFEE ESEDIKEQVK NDALKLKNIS GEEHIESSSK 720
LIFIDKLLCQ LHYENCKYVK NYASSYEKHK KEVAAYNYHK IQEQTNAQKK KREHSGKFKK 780
IEALENSPLF MEIYNKGKFD LKPTSQKEDM LKSFMHSVPV DNECPYKKKR CIYDKVKEYV 840
KNNSNIKHKG RARLISDNNK NNKNDDNSDD EDDDEEEDEV NYYNKRKDKK KKVISDDDDD 900
DDDDENSNDD NKSEDNNNDD NNNDDNKDIT KNDNNGNFSD NNNNNNNIND DQNDDNIFSL 960
HDSSKINNNI KEFLKSEKME MSNNTDKINE DSTVGVTDKG DNKLDDFDML KREEKEKNDA 1020
YMKEEGEEYD EEDVITHKNG TQLNIDNNNN NNNNINNVTD LKLQTDEKKV VINIKNEMND 1080
NDENGEKLGE AKMHKVLIFT QFQLVLDELE EYCKYRCWKY MRLDGSTNKL IRELDIREFN 1140
LSDSIYFIYL ISTRAGGLGI NLTAANHVIM YDEDWNPFID LQAIDRAHRI GQKREVNVWK 1200
LMTEWTVEER MAFRREQKLK LDKLVVQTQD DEDMLDNFEE KLSSDEIRKL MLHGKAAIQN 1260
MDVESTNNFP LEFFIERGRQ KLPIINGVDL EREEKCAIEE EINKKDDGDD ILVSKNDEDD 1320
DDDDDNSVDA KYNNNNDDDN AIDIDEVMMD EAEELESRNN NTNNNNNNND GTGGSGEMIN 1380
GQFSSSNNQN NNNNNNNNND ISLWRSVRER KKPQILYTPE YWGRKQEVKQ IKHEYRCFIC 1440
NNTKNHKAIV KDRNGNDIEI DYGDMINCFR CPKTYHKLCE GIKDENVKKT WTCSWHECCL 1500
CFRKSSQCGN LLIHCATCPT SFCYNCFPPD YVRYYVGEEY YHNLRQRGVN FTPQNWVCFL 1560
CSKCKAVEEQ KKRRKMTKEE RENEKQLQKE LRSQLHDSKQ EELEAKKRKR AQQLERDKFI 1620
IENRKRIDAL DQQYEDQLRK AYENVFPNNF VKELVNRIEH AKMLKQKGIV EDNNNNNNNN 1680
KETNKKKSTT FLHTKLPSKL LVLCENCKLP CHANYKYPGK CCYPPELDKS YYMSNTSFSQ 1740
MGRDGFEKRV SEGKNDSCSS HIHFKDKVGE DSNNMKNITN IVDGNKIMNS SPHKGGTKCE 1800
PNEGSTTPSR NDGIKKDLMV TSTINNNNSN NNNNSNNNNN NNNSYNFNEN KENSSSTNKL 1860
MSNKGIEYNK NDDEDYNNNE SKDKIMKGVG TTFLSDGSMR FEKDSPENNM NENNNMNNNN 1920
NNEKDSPQNN NDNTSKSKTR KFLRAVCSKC GTVQLGKLAH FRKHCDKLTE EEKKEYDEKR 1980
EKLKELINLL NKKKIKEEHT EEEYKNMSVF KFKSLYSNYQ DKADDILEDC IRSMKWDILI 2040
ADKKKIIKKE KEKENKKIYS KNDDDNNNNN NNNNKKNNNI TSMSLKAKLT HFLSNQPLTI 2100
SSDYSDTKDI IEIRSDLTDD MKEKINDELC TISGKRKKCI VKNIKKVKKK KGNDDNDENN 2160
NNSNNNVDGD KKNNNKSNTS SKKKDDKDLK KLNLLINPFH EKLIKDTHNA NFIRDSFNED 2220
FLNKAKEFLR VTKSNLINNG NNNNNNKNKK SSSNSKNINK NSSNTKNSSN TKSSSNTKSS 2280
SNTKNKNNKN NHNNSFLESA TTAEDFLRGI TTGNNNIFNL VSSSNSPYDK NKKLKDDEFE 2340
KSIIQNYLNK MKNSLKNSSH LDKNTIKEKL KELNYVNSRS NSNTKNNMNT NIINNNNNNN 2400
NNQHTISAQE NSLRFAKEIF KNGAFDKNGN FKLYANKGNL CNTNKDIVHL LKSNEQIENM 2460
NKNSGYSIND FNLDIFNIDK NIKCEDLEKK LLNLCASTNL MNKKNIQHDN NKKEDNKNYM 2520
LDSKNKNKQF LFKKDNTQQQ EAFLSNISKA KKESSNSRKR VVEDVNVDYD IKKITNTSEN 2580
SGPNKVQEYI LYRRNTSSVM SNVINNNDKS KNVRNDDEDD DDDEDDDEED DEDKNESSNY 2640
NNNKKKKTNT SSRNSSNNNS SNKNKNNKSG NDIHQASNLL YQNLLNNPQS LLQHLNLEDV 2700
KNFLKAADRS NNDNLPEIN 2719 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008026; F:ATP-dependent helicase activity; ISS:GeneDB_Pfalciparum.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003723; F:RNA binding; ISS:GeneDB_Pfalciparum.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR000330; SNF2_N.
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF00271; Helicase_C
 PF00628; PHD
 PF00176; SNF2_N 
SMART
 SM00487; DEXDc
 SM00490; HELICc
 SM00249; PHD
 SM00184; RING 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2
 PS50089; ZF_RING_2 
PRINTS