| Tag | Content |
|---|
| CPLM ID | CPLM-014854 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ethylmalonyl-CoA decarboxylase |
Protein Synonyms/Alias | Enoyl-CoA hydratase domain-containing protein 1; Methylmalonyl-CoA decarboxylase; MMCD |
Gene Name | Echdc1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 51 | GGSIDLQKKQNGIGI | acetylation | [1] | | 209 | KVLSGTFKLDSKEAL | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Decarboxylases ethylmalonyl-CoA decarboxylase, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activityx at lower level (By similarity). |
Sequence Annotation | |
Keyword | Complete proteome; Cytoplasm; Direct protein sequencing; Lyase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 299 AA |
Protein Sequence | MAKSLLASSL SVRTKILQTG VSLYNTTHGF HEEEVKKILE QFPGGSIDLQ KKQNGIGILT 60
LNNSNKMNAF SGAMMLQLLE RVIELENWTE GKGLIVHGAK NTFCSGSDLN AVKALSTPEN 120
GVALSMFMQN TLTRFMRLPL ISVALVQGWA MGGGAELTTA CDFRLMTEES VIRFVHKEMG 180
IVPSWGGASR LVEIIGSRQA LKVLSGTFKL DSKEALRIGL ADEVLQPSDE ATALEQAQEW 240
LEQFVSGPAQ VIRGLKKSVC SGRELYLEEA LQNERDVLET LWGGPANLEA IAKKGKHTK 299 |
Gene Ontology | GO:0005829; C:cytosol; ISS:UniProtKB. GO:0016831; F:carboxy-lyase activity; ISS:UniProtKB. GO:0004492; F:methylmalonyl-CoA decarboxylase activity; IEA:EC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |