CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038294
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 La-related protein 4 
Protein Synonyms/Alias
  
Gene Name
 Larp4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
160ANMEEIKKLTTNTDLubiquitination[1]
183PMVQVDEKGEKVRPSubiquitination[1]
211TTPVEEVKALFKNENubiquitination[1]
215EEVKALFKNENCPKVacetylation[2]
275AINTFFAKNGYRLMDubiquitination[1]
619SYAEVCQKPPKEPSPacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 718 AA 
Protein Sequence
MALEQVTSKG TGLNPNAKVW QEIPSGNPDG TPVTEPSWHE TAATSGSHPE GHTELSEDMC 60
KEYEVMYSPS CETTRNTADV EESADGMILG PEDLSYQLYD VSGESSSAIS TEDLKECLKK 120
QLEFCFSREN LSKDLYLISQ MDSDQFVPIW TVANMEEIKK LTTNTDLILE VLRSSPMVQV 180
DEKGEKVRPS HKRCIVILRE IPETTPVEEV KALFKNENCP KVISCEFAHN SNWYITFQSD 240
TDAQQAFKYL REEVKTFQGK PIMARIKAIN TFFAKNGYRL MDSSMYTQPI QTPTQYPSPV 300
FMQPVYNPQQ YSVYSLVPQS WSPSPAPYFE TPLAPFPNGS FVNGFSSPGS YKTNAAAMNM 360
GRPFPKNRVK PHFRSSSGSE HSTEGSVSLG DGPLSRSSSR IFLSERHNPT VTGQQEQTYL 420
PKEAPILQME QNGDFGRGRR TLFRGRRRRD DDRIPRPQPA ATEAKAPTPK FDLLATNFPP 480
LPGSSSRVPD ELGLENRMSD VVKGVCREKD SEDVRVSCPV PAEDGQTDCT SAPLSISPSP 540
PCTAEPPVLS TTQQEQDQME DSAVPKDTLN PVAVPVSSPT ATKPSPANTA SPCTSNINPP 600
RAVALQEPRK LSYAEVCQKP PKEPSPVLVQ PLRELRSNAV SPTRNEENGA PEKPVEKPHE 660
KPETRASKDH SGFRGNTIPR GAAGKIREQR RQFSHRATPQ GVTRRNGKEQ YVPPRSPK 718 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR006630; Lupus_La_RNA-bd.
 IPR000504; RRM_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF05383; La 
SMART
 SM00715; LA
 SM00360; RRM 
PROSITE
 PS50961; HTH_LA 
PRINTS