CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003363
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycerol-3-phosphate regulon repressor 
Protein Synonyms/Alias
  
Gene Name
 glpR 
Gene Synonyms/Alias
 b3423; JW3386 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
78KATQTEEKERIARKVacetylation[1]
210MLVVDHSKFGRNAMVacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Repressor of the glycerol-3-phosphate regulon. 
Sequence Annotation
 DOMAIN 3 58 HTH deoR-type.
 DNA_BIND 20 39 H-T-H motif (By similarity).  
Keyword
 Complete proteome; Direct protein sequencing; DNA-binding; Glycerol metabolism; Reference proteome; Repressor; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 252 AA 
Protein Sequence
MKQTQRHNGI IELVKQQGYV STEELVEHFS VSPQTIRRDL NELAEQNLIL RHHGGAALPS 60
SSVNTPWHDR KATQTEEKER IARKVAEQIP NGSTLFIDIG TTPEAVAHAL LNHSNLRIVT 120
NNLNVANTLM VKEDFRIILA GGELRSRDGG IIGEATLDFI SQFRLDFGIL GISGIDSDGS 180
LLEFDYHEVR TKRAIIENSR HVMLVVDHSK FGRNAMVNMG SISMVDAVYT DAPPPVSVMQ 240
VLTDHHIQLE LC 252 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0000986; F:bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding; IDA:EcoCyc.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:EcoCyc.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR014036; DeoR_C.
 IPR001034; HTH_DeoR_N.
 IPR018356; Tscrpt_reg_HTH_DeoR_CS.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00455; DeoRC
 PF08220; HTH_DeoR 
SMART
 SM00420; HTH_DEOR 
PROSITE
 PS00894; HTH_DEOR_1
 PS51000; HTH_DEOR_2 
PRINTS
 PR00037; HTHLACR.