CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010091
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Chromosome partition protein Smc 
Protein Synonyms/Alias
 Protein P115 homolog 
Gene Name
 smc 
Gene Synonyms/Alias
 p115; MPN_426; MP415 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
698SIKLAEAKTADLRALacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 Required for chromosome condensation and partitioning (By similarity). 
Sequence Annotation
 NP_BIND 33 40 ATP (By similarity).  
Keyword
 ATP-binding; Coiled coil; Complete proteome; Cytoplasm; DNA-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 982 AA 
Protein Sequence
MVFLKRFRAY GFKSYADEIT INFTHSMTGI VGPNGSGKSN VVDALKWVLG ERSMKHLRSK 60
SGDDMIFFGS KDKPASKLAE VELTFDNSQK LLHDPRPEIS VMRRIYRGSG QSEYYINGEL 120
VTLKEISGIF ADIGLEKGSL GIISQGSVSW FVEAKPEERR KIFEDASGIG RYTKRKEEVT 180
NQLARTVQNL KQVSIVLNEL KKDLKKLTIQ ADKAQRFVKL KEELKELELS VLVADYLKSQ 240
GELDRFNHQI GYIEQDFKLH EPQLQLLEDQ LNIFNQRFRD ADEQSIKLQQ ELQAVYQTIN 300
ELEQRKAVID VQLKNELSKK DEKHKIQALK KLIRVDQAQL ESLQAQVLKT TSEITLLTNE 360
LSTVQTELDT TKLNLNQNSA ALVYQQAQQE FLKAQNEEWV KTNPAHVLVK NVKALTGLLN 420
TLNTFLKFEK QYEKALLKAL GKSIGYLVVN NNLAALKAID FLLTNQIGQV TFLPIDDIAF 480
DTKIAPEHME ILQQLDGFLG VGSDHVSCDE SLQPIVNALL GQVIIASDLQ AALKLSSYTY 540
KLYRVVTLNG ETVYAGGIIQ GGYVKDNLSL YNLQEKLASS EANITQLEHN EKQLRTNLTS 600
LETKLNELNK KLKYEEILLE KFNERVNHTN KAILSYKIEY EQLTNESFDG TPHSFDETRL 660
VESLNRAWAE RDELNSQLKL NQELKETLAK SIKLAEAKTA DLRALLDEQR SQLVLAREGK 720
IRFENTIHNI TDKINGGYKL TMEFAIANYN KPIKLSTMQA QNKIARMQSQ LDEMGPINLE 780
SIAEIADKQK RFDDINGEYE SLQTAIKDLQ TAIGEIDELA CKEFDELIQK VNAELPKTFN 840
YLFGGGSCQI RYTDTDNVLL SGIEVFANPP GKNVANLMLL SGGEKTLVAL SVLFSILRVS 900
AFPLVILDEA ESALDPANVE RFANIIGNSS NNTQFLIITH RQGTMMKCDM LLGAAMQTKG 960
VTKTFAVSLE KAEQYISKDK QN 982 
Gene Ontology
 GO:0005694; C:chromosome; IEA:InterPro.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0003677; F:DNA binding; IEA:HAMAP.
 GO:0030261; P:chromosome condensation; IEA:InterPro.
 GO:0006310; P:DNA recombination; IEA:InterPro.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0006260; P:DNA replication; IEA:HAMAP.
 GO:0007062; P:sister chromatid cohesion; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR003395; RecF/RecN/SMC.
 IPR024704; SMC.
 IPR010935; SMC_hinge.
 IPR011890; SMC_prok. 
Pfam
 PF06470; SMC_hinge
 PF02463; SMC_N 
SMART
 SM00968; SMC_hinge 
PROSITE
  
PRINTS