UniProt Accession

 DYL2_RAT; Q78P75 

Genbank Protein ID

 AY034383; BC061874 

Genbank Nucleotide ID

 AAK57536.1; AAH61874.1 

Protein Name

 Dynein light chain 2, cytoplasmic 

Protein Synonyms/Alias

 Dynein light chain LC8-type 2 

Gene Name

 Dynll2 

Gene Synonyms/Alias

 Dlc2 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
9	SDRKAVIKNADMSED	acetylation	[1]
36	MEKYNIEKDIAAYIK	acetylation	[1]
43	KDIAAYIKKEFDKKY	acetylation	[1]
44	DIAAYIKKEFDKKYN	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Dynein; Microtubule; Motor protein; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 89 AA 

Protein Sequence

Gene Ontology

 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0016459; C:myosin complex; IEA:Compara.
 GO:0008092; F:cytoskeletal protein binding; IDA:RGD.
 GO:0003774; F:motor activity; IEA:UniProtKB-KW.
 GO:0007017; P:microtubule-based process; IEA:InterPro.
 GO:0008039; P:synaptic target recognition; IEP:RGD.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 

Interpro

 IPR019763; Dynein_light_1/2_CS.
 IPR001372; Dynein_light_chain_typ-1/2. 

Pfam

 PF01221; Dynein_light 

SMART

  

PROSITE

 PS01239; DYNEIN_LIGHT_1 

PRINTS