| Tag | Content |
|---|
| CPLM ID | CPLM-005737 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Alanine racemase, catabolic |
Protein Synonyms/Alias | |
Gene Name | dadX |
Gene Synonyms/Alias | alnB; dadB; b1190; JW1179 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 107 | VHSNWQLKALQNARL | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA (By similarity). |
Sequence Annotation | ACT_SITE 35 35 Proton acceptor; specific for D-alanine
ACT_SITE 253 253 Proton acceptor; specific for L-alanine
BINDING 130 130 Substrate (By similarity).
BINDING 301 301 Substrate; via amide nitrogen (By
MOD_RES 35 35 N6-(pyridoxal phosphate)lysine (By |
Keyword | Complete proteome; Isomerase; Pyridoxal phosphate; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 356 AA |
Protein Sequence | MTRPIQASLD LQALKQNLSI VRQAATHARV WSVVKANAYG HGIERIWSAI GATDGFALLN 60
LEEAITLRER GWKGPILMLE GFFHAQDLEI YDQHRLTTCV HSNWQLKALQ NARLKAPLDI 120
YLKVNSGMNR LGFQPDRVLT VWQQLRAMAN VGEMTLMSHF AEAEHPDGIS GAMARIEQAA 180
EGLECRRSLS NSAATLWHPE AHFDWVRPGI ILYGASPSGQ WRDIANTGLR PVMTLSSEII 240
GVQTLKAGER VGYGGRYTAR DEQRIGIVAA GYADGYPRHA PTGTPVLVDG VRTMTVGTVS 300
MDMLAVDLTP CPQAGIGTPV ELWGKEIKID DVAAAAGTVG YELMCALALR VPVVTV 356 |
Gene Ontology | GO:0008784; F:alanine racemase activity; IDA:EcoCyc. GO:0030170; F:pyridoxal phosphate binding; IEA:HAMAP. GO:0006522; P:alanine metabolic process; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |