CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027696
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Pcdha9 
Protein Synonyms/Alias
 Protocadherin alpha C2 
Gene Name
 Pcdhac2 
Gene Synonyms/Alias
 Pcdha1; Pcdha9 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
757RCPAELYKQANNNIDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity). 
Sequence Annotation
  
Keyword
 Calcium; Cell adhesion; Cell membrane; Complete proteome; Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1006 AA 
Protein Sequence
MEQAGARPGA TEHPRPLRPL PWLLLLSFRL LLVLLPGPAA SQLRYSVPEE QSPGALVGNV 60
ARALGLELRR LGPGCLRINH LGAPSPRYLE LDLTNGALFV NERIDREALC EQRPRCLLSL 120
EVLAHNPVAV SAIEVEILDI NDNSPRFPRP DYQLQVSESV APGARFHIES AQDPDVGANS 180
VQTYELSPSE HFELDLKPLQ ENSKVLELVL RKGLDREQTA LHYLVLTAVD GGIPARSGTA 240
QIAVRVLDTN DNSPAFDQST YRVQLREDAP PGTLVVKLNA SDPDEGSNGE LRYSLSSYTS 300
DRERQLFSID VTTGEVRVSG TLDYEESSSY QIYVQATDRG PVPMAGHCKV LVDIIDVNDN 360
APEVVLTDLY SPVPEDVALN TVVALLSVND QDSGSNRKVS LGLEASLPFR LNGFGNSYTL 420
VVSGPLDRER VAAYNITVTA TDGGVPPLTS QRTLQVEISD INDNPPSFLK DSYSIYIEEN 480
NLPGVLLCTV QATDPDQKEN AEVTYSLLDR EIQGLPVTSY VSINSASGSL YAVNSFDYEK 540
FREFFVTVEA QDKGRPPLSS TVTANVYVVD VNDHAPHILY PTSTNTSAAI EMVPRTAPAG 600
YLVTKVIAMD SDSGQNAWLF YHLVPTSDSD LFKVELHTGE IRITRKIGDE SGTTFNLTVV 660
VRDNGEPPLS ATVAITVAVV DRVSKMLPDT QRHIKSPRTY SEITLYLIIA LSTVSFIFLL 720
TIIVLSIIKC YRYTAYGTAC CGGFCGVRER CPAELYKQAN NNIDARIPHG LKVQPHFIEV 780
RGNGSLTKTY CYKACLTAGS GSDTFMFYNT GAQTGPGPGG AQASVTDNRQ LTGQSRHSTG 840
NLIILKNDAG SQNEPRQPNP DWRYSASLRA GMHSSVHLEE AGILRAGPGG PDQQWPTVSS 900
ATPEPEAGEV SPPVGAGVNS NSWTFKYGPG NPKQSGPGEL PDKFIIPGSP AIISIRQEPA 960
NNQIDKSDFI TFGKKEETKK KKKKKKGNKT QEKKEKGNST TDNSDQ 1006 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0007156; P:homophilic cell adhesion; IEA:InterPro. 
Interpro
 IPR002126; Cadherin.
 IPR015919; Cadherin-like.
 IPR020894; Cadherin_CS.
 IPR013164; Cadherin_N. 
Pfam
 PF00028; Cadherin
 PF08266; Cadherin_2 
SMART
 SM00112; CA 
PROSITE
 PS00232; CADHERIN_1
 PS50268; CADHERIN_2 
PRINTS
 PR00205; CADHERIN.