CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024982
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heterogeneous nuclear ribonucleoprotein A/B 
Protein Synonyms/Alias
 Heterogeneous nuclear ribonucleoprotein A/B, isoform CRA_a; S1 protein C2 
Gene Name
 Hnrnpab 
Gene Synonyms/Alias
 Hnrpab; mCG_6983 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
76KNEEDAGKMFVGGLSubiquitination[1]
88GLSWDTSKKDLKDYFubiquitination[1]
92DTSKKDLKDYFTKFGacetylation[2]
92DTSKKDLKDYFTKFGsuccinylation[2]
92DTSKKDLKDYFTKFGubiquitination[1]
97DLKDYFTKFGEVVDCacetylation[3]
97DLKDYFTKFGEVVDCubiquitination[1]
107EVVDCTIKMDPNTGRubiquitination[1]
124GFGFILFKDSSSVEKubiquitination[1]
131KDSSSVEKVLDQKEHacetylation[3]
131KDSSSVEKVLDQKEHubiquitination[1]
160MKKDPVKKIFVGGLNacetylation[3]
160MKKDPVKKIFVGGLNubiquitination[1]
174NPEATEEKIREYFGQacetylation[2, 3]
174NPEATEEKIREYFGQsuccinylation[2]
174NPEATEEKIREYFGQubiquitination[1]
195IELPIDPKLNKRRGFacetylation[2]
195IELPIDPKLNKRRGFubiquitination[1]
220VKKVLEKKFHTVSGSacetylation[2, 3]
228FHTVSGSKCEIKVAQacetylation[3]
228FHTVSGSKCEIKVAQubiquitination[1]
237EIKVAQPKEVYQQQQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Ribonucleoprotein; Viral nucleoprotein; Virion. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 332 AA 
Protein Sequence
MSDAAEEQPM ETTGATENGH EAAPEGEAPV EPSAAAAAPA ASAGSGGGTT TAPSGNQNGA 60
EGDQINASKN EEDAGKMFVG GLSWDTSKKD LKDYFTKFGE VVDCTIKMDP NTGRSRGFGF 120
ILFKDSSSVE KVLDQKEHRL DGRVIDPKKA MAMKKDPVKK IFVGGLNPEA TEEKIREYFG 180
QFGEIEAIEL PIDPKLNKRR GFVFITFKEE DPVKKVLEKK FHTVSGSKCE IKVAQPKEVY 240
QQQQYGSGGR GNRNRGNRGS GGGQSQSWNQ GYGNYWNQGY GYQQGYGPGY GGYDYSPYGY 300
YGYGPGYDYS QGSTNYGKSQ RRGGHQNNYK PY 332 
Gene Ontology
 GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
 GO:0003676; F:nucleic acid binding; IEA:UniProtKB-KW.
 GO:0000166; F:nucleotide binding; IEA:InterPro. 
Interpro
 IPR012956; CARG-binding_factor_N.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF08143; CBFNT
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS