CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028183
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG7441, isoform A 
Protein Synonyms/Alias
 CG7441, isoform B; FI03887p 
Gene Name
 CG7441-RA 
Gene Synonyms/Alias
 CG7441; Dmel_CG7441 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
347AATLDTAKYKDRVAEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Ligase; Nucleotide-binding; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 665 AA 
Protein Sequence
MFRFGKLHRS LSKVAKKGQT AVYSQRRCIQ ARSFLPGLAS RTAGTPSATA QVTGGNKQHV 60
HPHGNSVNSG HEEHNTRWPR KVFSGIQPTG SLHLGNYLGA VRKWVQLQNA RDDVTVCIVD 120
LHSITMPHNP PLLRENIFTM AATLLACGID PTKSTLFVQS AVAEHAEFNW ILSSLTTMPR 180
LAQLPQFREK SRLLKDVPLG LYVYPVLQAA DIMLYKSTHV PVGADQIQHI QLAQHLARIY 240
NGRYGETFPV CTAIIEDGDA SRVLSLRDPS KKMSKSEANP KATINLCDSP DLITQKIKKA 300
VTDFTSDITY NPGKRAGVSN LVNIHAQVTG QSIKTVVNEA ATLDTAKYKD RVAEAVVEHL 360
RPIREQIHHH MTKRNEMIYL LEVGAEKARQ QARQTLNDVK QRLGLGTSAN IPAAVHVAPL 420
LPAPDISKTS ASRRMSKDFD GNVHERHERM YGFGDQPSGG AGQSATGEVA DMPQAVVPRV 480
IRRAPIVPTQ SMRVEKQLGS TRTRHVFQMD TCNAPHIGFK PPPGFSASMV TGALAKNKRA 540
TVKPVTGNLG FGQQSQGGSY KHSQNVNPSA VSTIAREVNA AKKQEFTCNP ALYGSALESL 600
SNSSRSSEKT NSTAGDSEFI IVASEEEEQA ASSEEQREEA EEEESGERER EKGERNATEA 660
TKVEI 665 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004830; F:tryptophan-tRNA ligase activity; IEA:EC.
 GO:0006436; P:tryptophanyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR001412; aa-tRNA-synth_I_CS.
 IPR002305; aa-tRNA-synth_Ic.
 IPR014729; Rossmann-like_a/b/a_fold.
 IPR002306; Trp-tRNA-ligase.
 IPR024109; Trp-tRNA-ligase_bac-type. 
Pfam
 PF00579; tRNA-synt_1b 
SMART
  
PROSITE
 PS00178; AA_TRNA_LIGASE_I 
PRINTS
 PR01039; TRNASYNTHTRP.