UniProt Accession

 PHF6_BOVIN; Q08DR0 

Genbank Protein ID

 BC123609 

Genbank Nucleotide ID

 AAI23610.1 

Protein Name

 PHD finger protein 6 

Protein Synonyms/Alias

  

Gene Name

 PHF6 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Bos taurus (Bovine) 

NCBI Taxa ID

 9913 

Lysine Modification

Position	Peptide	Type	References
273	KTVLQEIKRGKRMKC	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 May play a role in transcriptional regulation (By similarity). 

Sequence Annotation

 ZN_FING 79 131 PHD-type 1; degenerate.
 ZN_FING 277 329 PHD-type 2; degenerate.
 MOTIF 13 16 Nuclear localization signal (Potential).
 MOTIF 129 133 Nuclear localization signal (Potential).
 MOTIF 157 169 Nucleolar localization signal
 MOD_RES 138 138 Phosphoserine (By similarity).
 MOD_RES 145 145 Phosphoserine (By similarity).
 MOD_RES 155 155 Phosphoserine (By similarity).
 MOD_RES 199 199 Phosphoserine (By similarity).
 MOD_RES 358 358 Phosphothreonine (By similarity).  

Keyword

 Complete proteome; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 365 AA 

Protein Sequence

Gene Ontology

 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR001965; Znf_PHD. 

Pfam

  

SMART

 SM00249; PHD 

PROSITE

 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 

PRINTS